Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 19/20 | 0.53 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.44 |
| ▸ | C1R | P00736 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7180694 | 0.79 | C1R (0.36) | ELANEC1R | |
| SCHEMBL940408 | 0.73 | ELANE (0.34) | ELANE | |
| SCHEMBL2515687 | 0.71 | ELANE (0.46) | ELANE | |
| SCHEMBL282843 | 0.69 | ELANE (1.00) | ELANECTRB1C1R | |
| SCHEMBL6537314 | 0.69 | ELANE (1.00) | ELANECTRB1 | |
| SCHEMBL23295733 | 0.67 | ELANE (0.39) | ELANECTRB1 | |
| SCHEMBL8543622 | 0.67 | ELANE (0.70) | ELANECTRB1C1R | |
| SCHEMBL8016730 | 0.66 | ELANE (0.76) | ELANECTRB1C1R | |
| SCHEMBL8006834 | 0.65 | C1R (0.81) | ELANEC1R | |
| SCHEMBL10657051 | 0.65 | ELANE (1.00) | ELANECTRB1C1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003007955-A2 | BIPHENYL APURINIC/APYRIMIDINIC SITE ENDONUCLEASE INHIBITORS TO TREAT CANCER | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2003-01-30 | — | — | WO | disclosed |