Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C1R | P00736 | 7/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | KLK1 | P06870 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | C1S | P09871 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7182976 | 0.79 | ELANE (0.53) | C1RELANE | |
| SCHEMBL10600690 | 0.60 | POLB (0.43) | — | |
| SCHEMBL17950745 | 0.58 | PDPK1 (0.37) | C1RF2PLGKLK1PRSS1 | |
| SCHEMBL940408 | 0.58 | ELANE (0.34) | ELANE | |
| SCHEMBL4163891 | 0.58 | ACHE (0.40) | — | |
| SCHEMBL2400239 | 0.58 | MAPT (0.34) | — | |
| SCHEMBL18848334 | 0.58 | ALDH1A1 (0.36) | — | |
| SCHEMBL7331931 | 0.56 | C1R (0.35) | C1RELANE | |
| SCHEMBL21249169 | 0.56 | L3MBTL1 (0.47) | C1RF2PLGKLK1PRSS1 | |
| SCHEMBL18630258 | 0.55 | EGFR (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003007955-A2 | BIPHENYL APURINIC/APYRIMIDINIC SITE ENDONUCLEASE INHIBITORS TO TREAT CANCER | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2003-01-30 | — | — | WO | disclosed |