Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7182894 | 0.97 | TP53 (0.60) | TP53TLR8HTTSMN1; SMN2TSHR | |
| Hydrochloric Acid SCHEMBL7178828 | 0.97 | TP53 (0.60) | TP53TLR8HTTSMN1; SMN2TSHR | |
| Hydrochloric Acid SCHEMBL7173630 | 0.97 | TP53 (0.60) | TP53TLR8HTTSMN1; SMN2TSHR | |
| Hydrochloric Acid SCHEMBL7177348 | 0.97 | TP53 (0.60) | TP53TLR8HTTSMN1; SMN2TSHR | |
| Hydrochloric Acid SCHEMBL7171664 | 0.97 | TP53 (0.60) | TP53TLR8HTTSMN1; SMN2TSHR | |
| Hydrochloric Acid SCHEMBL7183151 | 0.97 | TP53 (0.60) | TP53TLR8HTTSMN1; SMN2TSHR | |
| SCHEMBL15796790 | 0.97 | TP53 (0.63) | TP53TLR8HTTSMN1; SMN2TSHR | |
| Hydrochloric Acid SCHEMBL7172205 | 0.96 | TP53 (0.66) | TP53TLR8HTTSMN1; SMN2GAA | |
| Hydrochloric Acid SCHEMBL7177476 | 0.94 | TP53 (0.64) | TP53TLR8HTTSMN1; SMN2GAA | |
| Hydrochloric Acid SCHEMBL7182580 | 0.94 | TP53 (0.64) | TP53TLR8HTTSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1367069-A1 | Process for homo-or copolymerization of conjugated diens | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-12-03 | — | — | EP | disclosed |