Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 18/20 | 0.39 |
| ▸ | CTSL | P07711 | 2/20 | 0.39 |
| ▸ | CTSB | P07858 | 2/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6463875 | 1.00 | CTSS (0.39) | CTSSCTSLCTSBCTSKLMNA | |
| SCHEMBL6062088 | 0.94 | CTSS (0.36) | CTSSCTSLCTSBCTSKLMNA | |
| SCHEMBL7048383 | 0.91 | LMNA (0.40) | CTSSLMNAHTTSMN1; SMN2CYP3A4 | |
| SCHEMBL6467213 | 0.87 | LMNA (0.38) | CTSSLMNAHTTSMN1; SMN2CYP3A4 | |
| SCHEMBL7044345 | 0.85 | CTSS (0.39) | CTSSCTSLCTSBCTSKLMNA | |
| SCHEMBL7042145 | 0.84 | CTSS (0.40) | CTSSCTSLCTSBCTSKLMNA | |
| SCHEMBL6062750 | 0.83 | EPHX2 (0.38) | CTSSLMNAHTTCYP3A4CYP2C9 | |
| SCHEMBL6464521 | 0.80 | CTSS (0.38) | CTSSCTSLCTSKLMNAHTT | |
| SCHEMBL7183010 | 0.79 | CTSS (0.37) | CTSSLMNAHTTSMN1; SMN2CYP3A4 | |
| SCHEMBL7042876 | 0.79 | CTSS (0.43) | CTSSCTSLCTSBCTSKLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6576630-B1 | Alkanoyl substituted benzooxazoles or naphthooxazoles | AXYS PHARMACEUTICALS, INC. | 2003-06-10 | — | — | US | disclosed |