Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NSD2 | O96028 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6112587 | 0.69 | — | — | |
| SCHEMBL20850421 | 0.69 | — | — | |
| SCHEMBL24338104 | 0.66 | DHFR (0.33) | — | |
| SCHEMBL29272001 | 0.65 | KDM4E (0.43) | KDM4EMAPTNSD2ADRA2AADRA2B | |
| SCHEMBL28252759 | 0.64 | MEN1 (0.41) | KDM4EMAPTNSD2ADRA2AADRA2B | |
| SCHEMBL9008263 | 0.62 | ALDH1A1 (0.42) | KDM4EMAPTNSD2ADRA2AADRA2B | |
| SCHEMBL29394860 | 0.61 | TRPA1 (0.32) | MAPT | |
| SCHEMBL30218263 | 0.61 | TRPA1 (0.32) | MAPT | |
| SCHEMBL29011576 | 0.61 | KDM4E (0.40) | KDM4EMAPTNSD2ADRA2AADRA2B | |
| SCHEMBL16422227 | 0.60 | LMNA (0.52) | MAPTADRA2AADRA2BADRA2CLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0487155-A1 | Substituted-2,3-dihydro-2-oxo-1,5-benzodiazepines and their use as fungicides | EASTMAN KODAK COMPANY (US) | 1992-05-27 | — | — | EP | claimed |
| EP-0487155-A1 | Substituted-2,3-dihydro-2-oxo-1,5-benzodiazepines and their use as fungicides | EASTMAN KODAK COMPANY (US) | 1992-05-27 | — | — | EP | disclosed |