Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15827818 | 0.88 | TSHR (0.50) | TSHRL3MBTL1CA12CA14LMNA | |
| SCHEMBL7783582 | 0.84 | TSHR (0.54) | TSHRL3MBTL1CA12CA14LMNA | |
| SCHEMBL27547594 | 0.82 | TSHR (0.56) | TSHRL3MBTL1CA12CA14LMNA | |
| SCHEMBL4294644 | 0.81 | TSHR (0.61) | TSHRL3MBTL1CA12CA14LMNA | |
| SCHEMBL25981499 | 0.79 | TSHR (0.58) | TSHRL3MBTL1CA12CA14LMNA | |
| SCHEMBL9606613 | 0.79 | TSHR (0.58) | TSHRL3MBTL1CA12CA14LMNA | |
| Iodide SCHEMBL10927526 | 0.78 | TSHR (0.56) | TSHRL3MBTL1CA12CA14LMNA | |
| SCHEMBL14956983 | 0.78 | TSHR (0.56) | TSHRL3MBTL1CA12CA14LMNA | |
| SCHEMBL11288927 | 0.77 | TSHR (0.50) | TSHRL3MBTL1CA12CA14LMNA | |
| SCHEMBL10062448 | 0.76 | TSHR (0.54) | TSHRL3MBTL1CA12CA14LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165464-B1 | PREPARATION OF SELECTIVELY FLUORINATED ORGANIC COMPOUNDS | F2 CHEMICALS LTD (GB) | 2003-08-20 | — | — | EP | disclosed |
| EP-1165464-A1 | PREPARATION OF SELECTIVELY FLUORINATED ORGANIC COMPOUNDS | F2 Chemicals Limited (GB) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000058241-A1 | PREPARATION OF SELECTIVELY FLUORINATED ORGANIC COMPOUNDS | F2 CHEMICALS LIMITED (GB) | 2000-10-05 | — | — | WO | disclosed |