Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7181549 | 0.84 | CA2 (0.46) | TSHRLMNAKMT2AMEN1CA12 | |
| SCHEMBL7183546 | 0.84 | TSHR (0.54) | TSHRLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL4294644 | 0.81 | TSHR (0.61) | TSHRLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL25981499 | 0.79 | TSHR (0.58) | TSHRLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL11288927 | 0.77 | TSHR (0.50) | TSHRLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL22660949 | 0.76 | TSHR (0.48) | TSHRLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL8432394 | 0.74 | TSHR (0.64) | TSHRLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL130826 | 0.74 | TSHR (0.64) | TSHRLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL7190105 | 0.74 | — | — | |
| SCHEMBL18654092 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140734-A1 | PREPARATION OF SELECTIVELY FLUORINATED ORGANIC COMPOUNDS | F2 Chemicals Limited (GB) | 2001-10-10 | — | — | EP | disclosed |
| WO-2001028959-A1 | PREPARATION OF SELECTIVELY FLUORINATED ORGANIC COMPOUNDS | F2 CHEMICALS LTD. (GB) | 2001-04-26 | — | — | WO | disclosed |