SCHEMBL7183657

SCHEMBL7183657

CCCCCCCCC(N)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SMPD1 P17405 4/20 0.38
FDPS P14324 2/20 0.38
CES2 O00748 2/20 0.38
LPAR1 Q92633 1/20 0.38
LPAR3 Q9UBY5 1/20 0.38
TSHR P16473 1/20 0.33
THRB P10828 1/20 0.33
FAAH O00519 7/20 0.32
CES1 P23141 6/20 0.32
MEN1 O00255 1/20 0.32
CYP1A2 P05177 1/20 0.32
KMT2A Q03164 1/20 0.32
HSD17B10 Q99714 1/20 0.32
GGPS1 O95749 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6280317 1.00 SMPD1 (0.38) SMPD1FDPSCES2LPAR1LPAR3
SCHEMBL7179149 1.00 SMPD1 (0.38) SMPD1FDPSCES2LPAR1LPAR3
SCHEMBL6277835 0.98 SMPD1 (0.39) SMPD1FDPSCES2LPAR1LPAR3
SCHEMBL6282230 0.91 FDPS (0.34) FDPS
SCHEMBL6281815 0.82 SMPD1 (0.43) SMPD1FDPSCES2LPAR1LPAR3
Octane SCHEMBL15156216 0.82 TSHR (0.50) CES2LPAR1LPAR3TSHRTHRB
Perflenapent SCHEMBL8935098 0.82 TSHR (0.50) CES2LPAR1LPAR3TSHRTHRB
Perflenapent SCHEMBL8935092 0.79 TSHR (0.44) CES2LPAR1LPAR3TSHRTHRB
Perflexane SCHEMBL17714361 0.79 TSHR (0.44) CES2LPAR1LPAR3TSHRTHRB
SCHEMBL23560381 0.78 CES2 (0.41) FDPSCES2LPAR1LPAR3TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1349653-A2 FLUORINATED ZWITTERIONIC COCATALYST ACTIVATORS FOR OLEFIN POLYMERIZATION ExxonMobil Chemical Patents Inc. (US) 2003-10-08 EP disclosed
WO-2002036639-A2 FLUORINATED ZWITTERIONIC COCATALYST ACTIVATORS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2002-05-10 WO disclosed