Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 4/20 | 0.45 |
| ▸ | PTK2 | Q05397 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 2/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7175841 | 0.97 | ACSS2 (0.50) | ACSS2CA12CA9KDRPTK2 | |
| Hydrochloric Acid SCHEMBL7173979 | 0.97 | ACSS2 (0.50) | ACSS2CA12CA9KDRPTK2 | |
| Hydrochloric Acid SCHEMBL7183283 | 0.97 | ACSS2 (0.50) | ACSS2CA12CA9KDRPTK2 | |
| Hydrochloric Acid SCHEMBL7181558 | 0.97 | ACSS2 (0.50) | ACSS2CA12CA9KDRPTK2 | |
| Hydrochloric Acid SCHEMBL7177258 | 0.97 | ACSS2 (0.50) | ACSS2CA12CA9KDRPTK2 | |
| Hydrochloric Acid SCHEMBL7176394 | 0.97 | ACSS2 (0.50) | ACSS2CA12CA9KDRPTK2 | |
| SCHEMBL12354513 | 0.84 | CA12 (0.66) | ACSS2CA12CA9KDRPTK2 | |
| Hydrochloric Acid SCHEMBL7180788 | 0.82 | ACSS2 (0.52) | ACSS2CA12CA9KDRPTK2 | |
| Hydrochloric Acid SCHEMBL7178625 | 0.81 | MEN1 (0.60) | KDRPTK2HSD17B10KDM4ENPC1 | |
| Hydrochloric Acid SCHEMBL7171156 | 0.79 | ACSS2 (0.52) | ACSS2CA12CA9KDRPTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1367069-A1 | Process for homo-or copolymerization of conjugated diens | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-12-03 | — | — | EP | disclosed |