Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMBR | P28336 | 14/20 | 0.42 |
| ▸ | GRPR | P30550 | 12/20 | 0.42 |
| ▸ | FPR1 | P21462 | 2/20 | 0.41 |
| ▸ | CCKBR | P32239 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6255139 | 1.00 | NMBR (0.42) | NMBRGRPRFPR1CCKBRAGTR1 | |
| SCHEMBL6252251 | 0.85 | NMBR (0.48) | NMBRGRPRFPR1CCKBRAGTR1 | |
| SCHEMBL6254308 | 0.83 | PGR (0.38) | — | |
| SCHEMBL6254175 | 0.81 | NMBR (0.53) | NMBRGRPRFPR1CCKBRAGTR1 | |
| SCHEMBL6252522 | 0.78 | NMBR (0.47) | NMBRGRPRFPR1CCKBRAGTR1 | |
| SCHEMBL6252529 | 0.78 | NMBR (0.47) | NMBRGRPRFPR1CCKBRAGTR1 | |
| SCHEMBL6253307 | 0.77 | TACR1 (0.41) | NMBRGRPRFPR1 | |
| SCHEMBL6810082 | 0.76 | NMBR (0.72) | NMBRGRPRFPR1AGTR1GPR65 | |
| SCHEMBL6252249 | 0.76 | NMBR (0.72) | NMBRGRPRFPR1AGTR1GPR65 | |
| SCHEMBL6253540 | 0.75 | NMBR (0.38) | NMBRGRPRFPR1CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1333824-A2 | TREATMENT OF SEXUAL DYSFUNCTION | Warner-Lambert Company LLC (US) | 2003-08-13 | — | — | EP | claimed |
| WO-2002040008-A2 | TREATMENT OF SEXUAL DYSFUNCTION WITH NON PEPTIDE BOMBESIN RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY LLC (US) | 2002-05-23 | — | — | WO | claimed |