Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.38 |
| ▸ | USP21 | Q9UK80 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6255139 | 0.83 | NMBR (0.42) | — | |
| SCHEMBL6254300 | 0.76 | RAB9A (0.35) | USP21MAPTRAB9AFOLH1L3MBTL1 | |
| SCHEMBL6994303 | 0.72 | ALDH1A1 (0.37) | PGRMAPTUSP2FOLH1ALDH1A1 | |
| SCHEMBL6251031 | 0.72 | ALDH1A1 (0.37) | PGRMAPTUSP2FOLH1ALDH1A1 | |
| SCHEMBL6255326 | 0.70 | NMBR (0.51) | MAPTMEN1KMT2AHTTLMNA | |
| SCHEMBL6252251 | 0.68 | NMBR (0.48) | — | |
| SCHEMBL6254285 | 0.66 | MAPT (0.46) | MAPTRAB9AMEN1KMT2ALMNA | |
| SCHEMBL7903988 | 0.62 | HTR2A (0.44) | PGRMAPTRAB9AALDH1A1MEN1 | |
| SCHEMBL10814638 | 0.60 | MAPT (0.42) | MAPTRAB9AFOLH1ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL10749326 | 0.59 | MAPT (0.41) | MAPTRAB9AFOLH1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1333824-B1 | TREATMENT OF SEXUAL DYSFUNCTION WITH BOMBESIN RECEPTOR ANTAGONISTS | WARNER LAMBERT CO (US) | 2005-09-07 | — | — | EP | disclosed |