Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 20/20 | 0.54 |
| ▸ | FKBP4 | Q02790 | 2/20 | 0.49 |
| ▸ | FKBP5 | Q13451 | 2/20 | 0.49 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7181869 | 1.00 | FKBP1A (0.54) | FKBP1AFKBP4FKBP5ABCC1 | |
| SCHEMBL7178021 | 0.95 | FKBP1A (0.52) | FKBP1AFKBP4FKBP5ABCC1 | |
| SCHEMBL7629572 | 0.87 | FKBP1A (0.53) | FKBP1AFKBP4FKBP5ABCC1 | |
| SCHEMBL7625150 | 0.79 | HRH3 (0.36) | FKBP1A | |
| SCHEMBL7175494 | 0.74 | RXRA (0.44) | — | |
| SCHEMBL7175491 | 0.74 | RXRA (0.44) | — | |
| SCHEMBL7623162 | 0.72 | RXRA (0.39) | — | |
| SCHEMBL14920732 | 0.71 | FKBP1A (0.72) | FKBP1AFKBP4FKBP5ABCC1 | |
| SCHEMBL16310214 | 0.71 | FKBP1A (0.80) | FKBP1AFKBP4FKBP5ABCC1 | |
| SCHEMBL16310241 | 0.71 | FKBP1A (0.95) | FKBP1AFKBP4FKBP5ABCC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0941112-B1 | METHODS AND COMPOSITIONS FOR STIMULATING NEURITE GROWTH USING COMPOUNDS WITH AFFINITY FOR FKBP12 IN COMBINATION WITH NEUROTROPHIC FACTORS | VERTEX PHARMA (US) | 2003-02-12 | — | — | EP | disclosed |