SCHEMBL7184466

SCHEMBL7184466

Cc1cc(N)cc(Sc2ccc(N)cc2C)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.43
TSHR P16473 2/20 0.43
PDE7A Q13946 1/20 0.41
PDE10A Q9Y233 1/20 0.38
CASP1 P29466 2/20 0.36
MAPT P10636 4/20 0.36
KDM4E B2RXH2 3/20 0.36
HPGD P15428 3/20 0.36
TUBB4A P04350 2/20 0.36
TUBB P07437 2/20 0.36
TUBA3C P0DPH7 2/20 0.36
TUBA1B P68363 2/20 0.36
TUBA4A P68366 2/20 0.36
TUBB4B P68371 2/20 0.36
TUBB3 Q13509 2/20 0.36
TUBB2A Q13885 2/20 0.36
TUBB8 Q3ZCM7 2/20 0.36
TUBA3E Q6PEY2 2/20 0.36
TUBA1A Q71U36 2/20 0.36
TUBA1C Q9BQE3 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31457287 0.81 PDE7A (0.60) ALDH1A1TSHRPDE7APDE10ACASP1
SCHEMBL7189836 0.81 PDE7A (0.60) ALDH1A1TSHRPDE7APDE10ACASP1
SCHEMBL7189506 0.80 ALDH1A1 (0.56) ALDH1A1TSHRPDE7APDE10ACASP1
SCHEMBL7194725 0.80 PDE7A (0.47) ALDH1A1TSHRPDE7APDE10ACASP1
SCHEMBL7187600 0.78 ALDH1A1 (0.63) ALDH1A1TSHRMAPTKDM4ETUBB4A
SCHEMBL5548843 0.78 MAPT (0.57) ALDH1A1TSHRPDE7APDE10ACASP1
SCHEMBL7188754 0.77 TSHR (0.58) ALDH1A1TSHRPDE7AMAPTKDM4E
SCHEMBL7184598 0.75 PDE7A (0.44) ALDH1A1TSHRPDE7APDE10ACASP1
SCHEMBL7183466 0.74 ALDH1A1 (0.46) ALDH1A1TSHRPDE7ACASP1MAPT
SCHEMBL20854802 0.74 PDE7A (0.52) ALDH1A1TSHRPDE7AMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11111345-B2 Prepreg and carbon fiber-reinforced composite material TORAY INDUSTRIES, INC. (JP) 2021-09-07 US disclosed
US-20170327657-A1 PREPREG AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES, INC. (JP) 2017-11-16 US disclosed
US-9765194-B2 Prepreg and carbon fiber-reinforced composite material TORAY INDUSTRIES, INC. (JP) 2017-09-19 US disclosed
EP-2878617-B1 PREPREG AND CARBON-FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES (JP) 2017-03-01 EP disclosed
US-20150210813-A1 PREPREG AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES, INC. (JP) 2015-07-30 US disclosed
EP-2878617-A1 PREPREG AND CARBON-FIBER-REINFORCED COMPOSITE MATERIAL Toray Industries, Inc. (JP) 2015-06-03 EP disclosed
US-20030064235-A1 Optical members made of polymide resins MITSUI CHEMICALS, INC. (JP) 2003-04-03 US disclosed
EP-1237015-A1 OPTICAL MEMBERS MADE OF POLYIMIDE RESINS Mitsui Chemicals, Inc. (JP) 2002-09-04 EP disclosed