SCHEMBL7189836

SCHEMBL7189836

Cc1cc(N)ccc1Sc1ccc(N)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE7A Q13946 6/20 0.60
CYP3A4 P08684 3/20 0.52
TSHR P16473 2/20 0.52
MAPK1 P28482 1/20 0.52
ALDH1A1 P00352 3/20 0.48
MAPT P10636 4/20 0.45
HPGD P15428 3/20 0.45
KDM4E B2RXH2 3/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
CYP1A2 P05177 1/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C19 P33261 1/20 0.45
PDE10A Q9Y233 1/20 0.43
PDE7B Q9NP56 1/20 0.42
HTT P42858 1/20 0.41
CASP1 P29466 2/20 0.41
PKM P14618 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31457287 1.00 PDE7A (0.60) PDE7ACYP3A4TSHRMAPK1ALDH1A1
SCHEMBL7891113 0.91 HPGD (0.53) PDE7ACYP3A4TSHRMAPK1ALDH1A1
SCHEMBL5548843 0.88 MAPT (0.57) PDE7ACYP3A4TSHRMAPK1ALDH1A1
SCHEMBL20854802 0.88 PDE7A (0.52) PDE7ACYP3A4TSHRMAPK1ALDH1A1
SCHEMBL9487284 0.87 CYP3A4 (0.56) PDE7ACYP3A4TSHRMAPK1ALDH1A1
SCHEMBL7189506 0.87 ALDH1A1 (0.56) PDE7ACYP3A4TSHRMAPK1ALDH1A1
SCHEMBL7184598 0.85 PDE7A (0.44) PDE7ACYP3A4TSHRMAPK1ALDH1A1
SCHEMBL27875480 0.84 ALDH1A1 (0.45) PDE7ACYP3A4TSHRMAPK1ALDH1A1
SCHEMBL7194725 0.82 PDE7A (0.47) PDE7ACYP3A4TSHRALDH1A1MAPT
SCHEMBL7184466 0.81 ALDH1A1 (0.43) PDE7ACYP3A4TSHRALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220017461-A1 DIAMINE COMPOUND, AND POLYIMIDE PRECURSOR AND POLYIMIDE FILM USING SAME LG CHEM, LTD. (KR) 2022-01-20 US disclosed
US-11111345-B2 Prepreg and carbon fiber-reinforced composite material TORAY INDUSTRIES, INC. (JP) 2021-09-07 US disclosed
US-20170327657-A1 PREPREG AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES, INC. (JP) 2017-11-16 US disclosed
US-9765194-B2 Prepreg and carbon fiber-reinforced composite material TORAY INDUSTRIES, INC. (JP) 2017-09-19 US disclosed
EP-2878617-B1 PREPREG AND CARBON-FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES (JP) 2017-03-01 EP disclosed
US-20150210813-A1 PREPREG AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES, INC. (JP) 2015-07-30 US disclosed
EP-2878617-A1 PREPREG AND CARBON-FIBER-REINFORCED COMPOSITE MATERIAL Toray Industries, Inc. (JP) 2015-06-03 EP disclosed
US-20030064235-A1 Optical members made of polymide resins MITSUI CHEMICALS, INC. (JP) 2003-04-03 US disclosed
EP-1237015-A1 OPTICAL MEMBERS MADE OF POLYIMIDE RESINS Mitsui Chemicals, Inc. (JP) 2002-09-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220017461-A1 DIAMINE COMPOUND, AND POLYIMIDE PRECURSOR AND POLYIMIDE FILM USING SAME SRM, PCNA, PUF60 PDE7A 3112/4885CYP3A4 4767/4885TSHR 4225/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.