Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | TP53 | P04637 | 2/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8026875 | 0.93 | TSHR (0.43) | THRBTSHR | |
| SCHEMBL8815469 | 0.89 | MEN1 (0.44) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL6926823 | 0.89 | THRB (0.55) | THRBTSHRALDH1A1 | |
| SCHEMBL5716610 | 0.87 | TSHR (0.41) | THRBTSHRALDH1A1 | |
| SCHEMBL27811842 | 0.86 | THRB (0.61) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL28269853 | 0.86 | TSHR (0.59) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL7758811 | 0.85 | — | — | |
| SCHEMBL3291042 | 0.83 | TSHR (0.52) | TSHRALDH1A1 | |
| SCHEMBL8026874 | 0.83 | TSHR (0.55) | THRBTSHRALDH1A1TP53HIF1A | |
| Acrylic Acid SCHEMBL21630257 | 0.82 | TSHR (0.48) | TSHRALDH1A1TP53HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0827995-B1 | Hot melt adhesives comprising low free monomer, low oligomer content isocyanate prepolymers | AIR PROD & CHEM (US) | 2003-11-12 | — | — | EP | disclosed |
| US-6280561-B1 | Hot melt adhesives comprising low free monomer, low oligomer isocyanate prepolymers | AIR PRODUCTS AND CHEMICALS, INC. | 2001-08-28 | — | — | US | disclosed |
| EP-0827995-A2 | Hot melt adhesives comprising low free monomer, low oligomer content isocyanate prepolymers | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1998-03-11 | — | — | EP | disclosed |
| EP-0092446-B1 | THERMALLY CURABLE OLEFINIC POLYMERS AND MANUFACTURING METHOD FOR CURED SHAPED OBJECTS MADE THEREOF | ELF ATOCHEM S.A. (FR) | 1987-12-16 | — | — | EP | disclosed |
| EP-0092446-A1 | Thermally curable olefinic polymers and manufacturing method for cured shaped objects made thereof | ELF ATOCHEM S.A. (FR) | 1983-10-26 | — | — | EP | disclosed |