Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 5/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7184471 | 0.89 | THRB (0.39) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL8026875 | 0.87 | TSHR (0.43) | THRBTSHR | |
| SCHEMBL9067424 | 0.87 | THRB (0.46) | MEN1KMT2ATHRBTSHRMAPK1 | |
| SCHEMBL27811842 | 0.85 | THRB (0.61) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL8899064 | 0.85 | MEN1 (0.41) | MEN1KMT2ATHRBTSHRMAPK1 | |
| SCHEMBL8145264 | 0.84 | THRB (0.41) | MEN1KMT2ATHRBTSHRALDH1A1 | |
| SCHEMBL25403843 | 0.84 | MEN1 (0.47) | MEN1KMT2ATHRBTSHRMAPK1 | |
| SCHEMBL11033121 | 0.84 | MEN1 (0.47) | MEN1KMT2ATHRBTSHRMAPK1 | |
| SCHEMBL5487190 | 0.83 | MEN1 (0.50) | MEN1KMT2ATHRBTSHRMAPK1 | |
| SCHEMBL6036910 | 0.82 | THRB (0.48) | MEN1KMT2ATHRBTSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997021097-A1 | USE OF POLYMERIC MATERIALS FOR SIMULATING SKIN, PARTICULARLY IN A DIFFUSION CELL | LVMH RECHERCHE (FR) | 1997-06-12 | — | — | WO | disclosed |