⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8789458 | 0.88 | — | — | |
| SCHEMBL148051 | 0.86 | — | — | |
| SCHEMBL11841545 | 0.86 | — | — | |
| SCHEMBL10672001 | 0.84 | — | — | |
| SCHEMBL3682247 | 0.80 | — | — | |
| SCHEMBL10674185 | 0.76 | — | — | |
| SCHEMBL11592080 | 0.70 | GSR (0.32) | — | |
| SCHEMBL11592077 | 0.70 | GSR (0.32) | — | |
| SCHEMBL11049355 | 0.70 | TSHR (0.33) | — | |
| SCHEMBL251470 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1317456-A2 | CYCLIC AND ACYCLIC AMIDINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM FOR USE AS PROGESTERONE RECEPTOR BINDING AGENTS | Bayer Corporation (US) | 2003-06-11 | — | — | EP | disclosed |
| WO-2002020526-A2 | CYCLIC AND ACYCLIC AMIDINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM FOR USE AS PROGESTERONE RECEPTOR BINDING AGENTS | BAYER PHARMACEUTICALS CORPORATION (US) | 2002-03-14 | — | — | WO | disclosed |
| CN-1287117-A | Cyclobutene derivatives, preparation method and therapeutic use thereof | SANKYO CO (JP) | 2001-03-14 | — | — | CN | disclosed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |
| US-5668178-A | VIRICIDE, BACTERICIDE, HIV | WARNER-LAMBERT COMPANY (US) | 1997-09-16 | — | — | US | disclosed |
| US-5643925-A | COGNITION ACTIVATORS AND NERVE GROWTH FACTORS | SANKYO COMPANY, LIMITED (JP) | 1997-07-01 | — | — | US | disclosed |
| US-5614521-A | NERVE GROWTH FACTOR | SANKYO COMPANY, LIMITED (JP) | 1997-03-25 | — | — | US | disclosed |
| EP-0501656-B1 | New benzene derivatives having (NGF) production-promoting activity | SANKYO CO (JP) | 1997-01-22 | — | — | EP | disclosed |
| US-5463122-A | Amido-phenylthiols or dithiobisbenzamides as bactericides, viricides, retrovirus antigrowth agents; AIDS | WARNER-LAMBERT COMPANY (US) | 1995-10-31 | — | — | US | disclosed |
| EP-0501656-A2 | New benzene derivatives having (NGF) production-promoting activity | Sankyo Company Limited (JP) | 1992-09-02 | — | — | EP | disclosed |