Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.53 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 8/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.36 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7176581 | 0.96 | MAOA (0.53) | MAOANR4A1MAPTRAB9AMAOB | |
| Hydrochloric Acid SCHEMBL7183501 | 0.96 | MAOA (0.53) | MAOANR4A1MAPTRAB9AMAOB | |
| Hydrochloric Acid SCHEMBL7182824 | 0.96 | MAOA (0.53) | MAOANR4A1MAPTRAB9AMAOB | |
| Hydrochloric Acid SCHEMBL7174436 | 0.96 | MAOA (0.53) | MAOANR4A1MAPTRAB9AMAOB | |
| Hydrochloric Acid SCHEMBL7173187 | 0.96 | MAOA (0.53) | MAOANR4A1MAPTRAB9AMAOB | |
| Hydrochloric Acid SCHEMBL7177585 | 0.96 | MAOA (0.53) | MAOANR4A1MAPTRAB9AMAOB | |
| Hydrochloric Acid SCHEMBL7180426 | 0.87 | NR4A1 (0.43) | MAOANR4A1MAPTRAB9AMAOB | |
| SCHEMBL6915046 | 0.85 | MAOA (0.42) | MAOANR4A1MAPTRAB9AMAOB | |
| SCHEMBL6915044 | 0.85 | MAOA (0.42) | MAOANR4A1MAPTRAB9AMAOB | |
| Hydrochloric Acid SCHEMBL7183402 | 0.84 | NR4A1 (0.43) | MAOANR4A1MAPTRAB9AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1367069-A1 | Process for homo-or copolymerization of conjugated diens | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-12-03 | — | — | EP | disclosed |