Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | VDR | P11473 | 2/20 | 0.44 |
| ▸ | PPARD | Q03181 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7194279 | 0.93 | CYP1A2 (0.47) | MAPTTDP1ALDH1A1VDRPPARD | |
| SCHEMBL7195351 | 0.90 | MAPT (0.47) | MAPTTDP1ALDH1A1L3MBTL1KDM4E | |
| SCHEMBL7183969 | 0.90 | ESR1 (0.43) | MAPTTDP1ALDH1A1L3MBTL1KDM4E | |
| SCHEMBL7183920 | 0.88 | FFAR1 (0.50) | VDRPPARDDGAT2MTNR1AMTNR1B | |
| SCHEMBL7194188 | 0.86 | ESR1 (0.45) | MAPTTDP1ALDH1A1VDRPPARD | |
| SCHEMBL7193901 | 0.86 | MAPT (0.45) | MAPTTDP1ALDH1A1VDRPPARD | |
| SCHEMBL7195102 | 0.84 | CYP4F2 (0.46) | MAPTALDH1A1L3MBTL1KDM4EGLA | |
| SCHEMBL7189999 | 0.84 | CYP4F2 (0.46) | MAPTTDP1ALDH1A1L3MBTL1KDM4E | |
| SCHEMBL7183821 | 0.84 | TDP1 (0.43) | MAPTTDP1ALDH1A1VDRPPARD | |
| SCHEMBL7185785 | 0.82 | CYP1A2 (0.52) | CYP1A2CYP3A4CYP2D6CYP2C9HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835867-B1 | 1-Aryloxy-2-arylnaphthyl compounds, intermediates, compositions, and methods | LILLY CO ELI (US) | 2003-12-03 | — | — | EP | claimed |