Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7181142 | 0.94 | CYP4F2 (0.43) | CYP4F2CYP4A11MAPTLMNAL3MBTL1 | |
| SCHEMBL7189037 | 0.94 | CYP4F2 (0.43) | CYP4F2CYP4A11MAPTLMNAL3MBTL1 | |
| SCHEMBL7193820 | 0.94 | ALOX5 (0.42) | CYP4F2CYP4A11MAPTLMNAL3MBTL1 | |
| SCHEMBL7194279 | 0.91 | CYP1A2 (0.47) | CYP4F2CYP4A11MAPTLMNAL3MBTL1 | |
| SCHEMBL7195351 | 0.90 | MAPT (0.47) | CYP4F2CYP4A11MAPTLMNAL3MBTL1 | |
| SCHEMBL7190395 | 0.89 | CYP1A2 (0.42) | CYP4F2CYP4A11MAPTLMNAL3MBTL1 | |
| SCHEMBL7188897 | 0.89 | ESR1 (0.43) | MAPTLMNAL3MBTL1ALDH1A1TDP1 | |
| SCHEMBL7194188 | 0.88 | ESR1 (0.45) | CYP4F2CYP4A11MAPTLMNAL3MBTL1 | |
| SCHEMBL7193207 | 0.88 | ESR1 (0.49) | CYP4F2CYP4A11ALDH1A1KDM4EMAOA | |
| SCHEMBL7188063 | 0.88 | ESR1 (0.44) | MAOAESR1ESR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835867-B1 | 1-Aryloxy-2-arylnaphthyl compounds, intermediates, compositions, and methods | LILLY CO ELI (US) | 2003-12-03 | — | — | EP | claimed |