Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25291696 | 0.85 | KMT2A (0.49) | KMT2AMEN1LMNAALDH1A1TDP1 | |
| SCHEMBL25247464 | 0.85 | KMT2A (0.49) | KMT2AMEN1LMNAALDH1A1TDP1 | |
| SCHEMBL25246326 | 0.82 | LMNA (0.51) | KMT2AMEN1LMNAALDH1A1TDP1 | |
| SCHEMBL25248042 | 0.82 | MEN1 (0.46) | KMT2AMEN1LMNAALDH1A1TDP1 | |
| SCHEMBL29379649 | 0.82 | KMT2A (0.46) | KMT2AMEN1LMNAALDH1A1TDP1 | |
| SCHEMBL25259070 | 0.82 | KMT2A (0.46) | KMT2AMEN1LMNAALDH1A1TDP1 | |
| SCHEMBL25251423 | 0.81 | MEN1 (0.45) | KMT2AMEN1LMNAALDH1A1TDP1 | |
| SCHEMBL25249147 | 0.81 | LMNA (0.46) | KMT2AMEN1LMNAALDH1A1TDP1 | |
| SCHEMBL25251704 | 0.81 | KMT2A (0.45) | KMT2AMEN1LMNAALDH1A1TDP1 | |
| SCHEMBL6537951 | 0.79 | KMT2A (0.51) | KMT2AMEN1LMNAALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6583150-B1 | Cytotoxic propertie; antitumor; pyrido-(3,2-g)quinoline-5,10-diones; benzo(b)pyrido(4,3,2-de)(1,7)-phenanthroline-8-ones | LABORATORIE L. LAFON (FR) | 2003-06-24 | — | — | US | disclosed |
| EP-1161432-A1 | PHARMACEUTICAL COMPOSITION BASED ON POLYAROMATIC COMPOUNDS | LABORATOIRE L. LAFON (FR) | 2001-12-12 | — | — | EP | disclosed |
| WO-2000055160-A1 | PHARMACEUTICAL COMPOSITION BASED ON POLYAROMATIC COMPOUNDS | LABORATOIRE L. LAFON (FR) | 2000-09-21 | — | — | WO | disclosed |