SCHEMBL7185259

SCHEMBL7185259

CCN(CC)c1ccc2c(c1)Oc1cc(C)c(Cl)cc1C2c1ccccc1C(=O)OC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.41
L3MBTL1 Q9Y468 4/20 0.41
LMNA P02545 4/20 0.41
NPSR1 Q6W5P4 4/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
TDP1 Q9NUW8 3/20 0.41
NPC1 O15118 2/20 0.41
ALDH1A1 P00352 7/20 0.40
HSD17B10 Q99714 4/20 0.40
MAPK1 P28482 4/20 0.40
ALOX15 P16050 1/20 0.40
RAB9A P51151 1/20 0.40
GHSR Q92847 3/20 0.39
CA12 O43570 1/20 0.39
CA9 Q16790 1/20 0.39
KMT2A Q03164 5/20 0.38
MEN1 O00255 4/20 0.38
ALOX12 P18054 1/20 0.38
HPGD P15428 2/20 0.37
POLB P06746 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7194575 0.92 MAPT (0.44) MAPTL3MBTL1LMNANPSR1SMN1; SMN2
SCHEMBL3890180 0.90 MAPT (0.48) MAPTL3MBTL1LMNANPSR1SMN1; SMN2
SCHEMBL8391027 0.88 CYP2C9 (0.47) MAPTL3MBTL1LMNANPSR1SMN1; SMN2
SCHEMBL7186463 0.88 MAPT (0.42) MAPTL3MBTL1LMNANPSR1SMN1; SMN2
SCHEMBL12923595 0.87 MAPT (0.45) MAPTL3MBTL1LMNANPSR1SMN1; SMN2
SCHEMBL9117348 0.87 MAPT (0.40) MAPTL3MBTL1LMNANPSR1SMN1; SMN2
SCHEMBL9114905 0.86 MAPT (0.40) MAPTL3MBTL1LMNANPSR1SMN1; SMN2
SCHEMBL9113560 0.86 MAPT (0.40) MAPTL3MBTL1LMNANPSR1SMN1; SMN2
SCHEMBL7179949 0.85 MAPT (0.41) MAPTL3MBTL1LMNANPSR1SMN1; SMN2
SCHEMBL9176269 0.85 MAPT (0.47) MAPTL3MBTL1LMNANPSR1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6586364-B2 Shell walls; liquid coloring PENTAX CORPORATION (JP) 2003-07-01 US disclosed
US-20020168580-A1 Heat-sensitive microcapsule and recording medium using same ASAHI KOGAKU KOGYO KABUSHIKI KAISHA 2002-11-14 US disclosed