Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | FABP3 | P05413 | 2/20 | 0.33 |
| ▸ | FABP4 | P15090 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7178521 | 0.97 | GABRA1 (0.34) | GABRA1GABRB2TDP1FABP3FABP4 | |
| Hydrochloric Acid SCHEMBL7176920 | 0.97 | GABRA1 (0.34) | GABRA1GABRB2TDP1FABP3FABP4 | |
| Hydrochloric Acid SCHEMBL7182194 | 0.97 | GABRA1 (0.34) | GABRA1GABRB2TDP1FABP3FABP4 | |
| Hydrochloric Acid SCHEMBL7180516 | 0.97 | GABRA1 (0.34) | GABRA1GABRB2TDP1FABP3FABP4 | |
| Hydrochloric Acid SCHEMBL7172124 | 0.97 | GABRA1 (0.34) | GABRA1GABRB2TDP1FABP3FABP4 | |
| Hydrochloric Acid SCHEMBL7179086 | 0.97 | GABRA1 (0.34) | GABRA1GABRB2TDP1FABP3FABP4 | |
| SCHEMBL16077911 | 0.97 | GABRA1 (0.36) | GABRA1GABRB2TDP1FABP3FABP4 | |
| Hydrochloric Acid SCHEMBL7174370 | 0.88 | GABRA1 (0.32) | GABRA1GABRB2GABRG2GABRB3FAAH | |
| Hydrochloric Acid SCHEMBL7175760 | 0.88 | GABRA1 (0.39) | GABRA1GABRB2TDP1GABRG2GABRB3 | |
| Hydrochloric Acid SCHEMBL7180672 | 0.85 | GABRA1 (0.32) | GABRA1GABRB2GABRG2GABRB3FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1367069-A1 | Process for homo-or copolymerization of conjugated diens | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-12-03 | — | — | EP | disclosed |