Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 11/20 | 0.53 |
| ▸ | MAOA | P21397 | 3/20 | 0.45 |
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5951296 | 0.84 | ACHE (0.59) | ACHEMAOAMAOBHTR2AHTR2C | |
| SCHEMBL5951482 | 0.83 | ACHE (0.53) | ACHEMAOAMAOBHTR2AHTR2C | |
| SCHEMBL16942508 | 0.81 | ACHE (0.42) | ACHEHTR2AHTR2CHTR2BHTR1A | |
| SCHEMBL3378780 | 0.81 | MAOA (0.62) | ACHEMAOAMAOBHTR2AHTR1A | |
| SCHEMBL5951495 | 0.79 | ACHE (0.52) | ACHEMAOAMAOBABCB1BRD4 | |
| SCHEMBL16290349 | 0.79 | HTR2A (0.42) | ACHEMAOAMAOBHTR2AHTR2C | |
| SCHEMBL26704407 | 0.79 | HTR2A (0.42) | ACHEMAOAMAOBHTR2AHTR2C | |
| SCHEMBL5951770 | 0.79 | ACHE (0.52) | ACHEMAOAMAOBDRD2ABCB1 | |
| SCHEMBL5951341 | 0.79 | ACHE (0.52) | ACHEMAOAMAOBHTR2AHTR2C | |
| SCHEMBL5952251 | 0.79 | ACHE (0.51) | ACHEMAOAMAOBHTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1022265-B1 | 2-Indanemethanol derivatives and their use as perfuming ingredients | FIRMENICH & CIE (CH) | 2003-03-26 | — | — | EP | disclosed |
| US-6323173-B1 | COMPOUNDS WHICH DEVELOP FRESH, HUMIC, VERY PLEASANT FRAGRANCE OF LILY OF THE VALLEY TYPE; GOOD STABILITY AND EXCELLENT TENACITY | FIRMENICH SA (CH) | 2001-11-27 | — | — | US | disclosed |
| EP-1022265-A1 | 2-Indanemethanol derivatives and their use as perfuming ingredients | FIRMENICH SA (CH) | 2000-07-26 | — | — | EP | disclosed |