Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RARB | P10826 | 2/20 | 0.41 |
| ▸ | RARG | P13631 | 2/20 | 0.41 |
| ▸ | RARA | P10276 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29965248 | 1.00 | ALDH1A1 (0.45) | ALDH1A1MAPTGAANPSR1MEN1 | |
| SCHEMBL7017316 | 1.00 | ALDH1A1 (0.45) | ALDH1A1MAPTGAANPSR1MEN1 | |
| SCHEMBL9266425 | 1.00 | ALDH1A1 (0.45) | ALDH1A1MAPTGAANPSR1MEN1 | |
| SCHEMBL4304302 | 0.85 | ALDH1A1 (0.49) | ALDH1A1MAPTGAANPSR1MEN1 | |
| SCHEMBL11492167 | 0.82 | ALDH1A1 (0.43) | ALDH1A1MAPTGAANPSR1MEN1 | |
| SCHEMBL15082362 | 0.81 | RARB (0.49) | ALDH1A1MAPTGAANPSR1MEN1 | |
| SCHEMBL14157557 | 0.81 | RARB (0.49) | ALDH1A1MAPTGAANPSR1MEN1 | |
| SCHEMBL3186206 | 0.80 | ALDH1A1 (0.44) | ALDH1A1MAPTGAANPSR1MEN1 | |
| SCHEMBL25229798 | 0.80 | ALDH1A1 (0.40) | ALDH1A1MAPTGAANPSR1MEN1 | |
| SCHEMBL17448809 | 0.79 | RARB (0.41) | ALDH1A1MAPTGAANPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1368014-A1 | USE OF CYCLOHEXENONE DERIVATIVES FOR THE MANUFACTURE OF A MEDICAMENT IN THE TREATMENT OF DYSURIA | Meiji Dairies Corporation (JP) | 2003-12-10 | — | — | EP | disclosed |
| EP-1368013-A1 | USE OF A CYCLOHEXENONE DERIVATIVES IN THE MANUFACTURE OF A MEDICAMENT FOR TREATING DIABETIC COMPLICATIONS | Meiji Dairies Corporation (JP) | 2003-12-10 | — | — | EP | disclosed |
| WO-2002066023-A1 | USE OF A CYCLOHEXENONE DERIVATIVES IN THE MANUFACTURE OF A MEDICAMENT FOR TREATING DIABETIC COMPLICATIONS | MEIJI DAIRIES CORPORATION (JP) | 2002-08-29 | — | — | WO | disclosed |
| WO-2002066024-A1 | USE OF CYCLOHEXENONE DERIVATIVES FOR THE MANUFACTURE OF A MEDICAMENT IN THE TREATMENT OF DYSURIA | MEIJI DAIRIES CORPORATION (JP) | 2002-08-29 | — | — | WO | disclosed |