Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | RARB | P10826 | 2/20 | 0.45 |
| ▸ | RARG | P13631 | 2/20 | 0.45 |
| ▸ | RARA | P10276 | 1/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7185668 | 0.85 | ALDH1A1 (0.45) | ALDH1A1MAPTGAANPSR1MEN1 | |
| SCHEMBL9266425 | 0.85 | ALDH1A1 (0.45) | ALDH1A1MAPTGAANPSR1MEN1 | |
| SCHEMBL29965248 | 0.85 | ALDH1A1 (0.45) | ALDH1A1MAPTGAANPSR1MEN1 | |
| SCHEMBL7017316 | 0.85 | ALDH1A1 (0.45) | ALDH1A1MAPTGAANPSR1MEN1 | |
| SCHEMBL4666701 | 0.83 | ALDH1A1 (0.44) | ALDH1A1MAPTGAANPSR1MEN1 | |
| SCHEMBL22627382 | 0.81 | MEN1 (0.59) | ALDH1A1MAPTGAANPSR1MEN1 | |
| SCHEMBL21574083 | 0.81 | MEN1 (0.46) | ALDH1A1MAPTGAANPSR1MEN1 | |
| SCHEMBL31502587 | 0.80 | ALDH1A1 (0.46) | ALDH1A1MAPTGAANPSR1MEN1 | |
| SCHEMBL3148661 | 0.79 | MEN1 (0.44) | ALDH1A1MAPTGAANPSR1MEN1 | |
| SCHEMBL3186206 | 0.78 | ALDH1A1 (0.44) | ALDH1A1MAPTGAANPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3164377-B1 | PRINS REACTION ON HINDERED SUBSTRATES | FIRMENICH & CIE (CH) | 2022-06-08 | — | — | EP | disclosed |
| CN-106488900-B | Prins reaction on hindered substrates | 弗门尼舍有限公司 | 2020-06-09 | — | — | CN | disclosed |
| US-9926249-B2 | Prins reaction on hindered substrates | FIRMENICH SA (CH) | 2018-03-27 | — | — | US | disclosed |
| US-20170145013-A1 | DIHYDROPTERIDINONE DERIVATIVES AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2017-05-25 | — | — | US | disclosed |
| US-20170129834-A1 | PRINS REACTION ON HINDERED SUBSTRATES | FIRMENICH SA (CH) | 2017-05-11 | — | — | US | disclosed |
| EP-3164377-A1 | PRINS REACTION ON HINDERED SUBSTRATES | Firmenich SA (CH) | 2017-05-10 | — | — | EP | disclosed |
| WO-2016001286-A1 | PRINS REACTION ON HINDERED SUBSTRATES | FIRMENICH SA (CH) | 2016-01-07 | — | — | WO | disclosed |
| WO-2011143651-A1 | COMPOSITIONS AND METHODS FOR MODULATING METABOLISM | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2011-11-17 | — | — | WO | disclosed |
| WO-2009114136-A2 | FENRETINIDE DERIVATIVES AND USES THEREOF AS THERAPEUTIC, DIAGNOSTIC AND IMAGING AGENTS | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2009-09-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170129834-A1 | PRINS REACTION ON HINDERED SUBSTRATES | ADH1C, ADH5, ADH1A | ALDH1A1 4/4885MAPT 2548/4885GAA 2987/4885 |
| US-20170145013-A1 | DIHYDROPTERIDINONE DERIVATIVES AND USES THEREOF | BRDT, BRD4, BRD3 | ALDH1A1 2824/4885MAPT 3666/4885GAA 1762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.