Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.51 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.49 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | WNK1 | Q9H4A3 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | BCL6 | P41182 | 1/20 | 0.43 |
| ▸ | BCOR | Q6W2J9 | 1/20 | 0.43 |
| ▸ | MERTK | Q12866 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8248585 | 0.92 | HCAR3 (0.59) | KMT2AMEN1L3MBTL1HCAR3KAT2B | |
| SCHEMBL7187372 | 0.89 | MEN1 (0.67) | KMT2AMEN1L3MBTL1HCAR3KAT2B | |
| SCHEMBL20333669 | 0.89 | KMT2A (0.63) | KMT2AMEN1L3MBTL1HCAR3KAT2B | |
| SCHEMBL4122997 | 0.88 | MEN1 (0.65) | KMT2AMEN1L3MBTL1HCAR3KAT2B | |
| SCHEMBL7182042 | 0.88 | MEN1 (0.65) | KMT2AMEN1L3MBTL1HCAR3KAT2B | |
| SCHEMBL7185961 | 0.86 | HCAR3 (0.56) | KMT2AMEN1L3MBTL1HCAR3KAT2B | |
| SCHEMBL7179398 | 0.86 | HCAR3 (0.53) | KMT2AMEN1L3MBTL1HCAR3KAT2B | |
| SCHEMBL7179403 | 0.86 | HCAR3 (0.53) | KMT2AMEN1L3MBTL1HCAR3KAT2B | |
| SCHEMBL7185959 | 0.86 | HCAR3 (0.56) | KMT2AMEN1L3MBTL1HCAR3KAT2B | |
| SCHEMBL7183448 | 0.85 | HCAR3 (0.52) | KMT2AMEN1L3MBTL1HCAR3KAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6582351-B1 | Benzimidazole heterocyclic compounds having pharmacological activities, and their use as a medicament for treatment or prevention of diseases mediated by cGMP-PDE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-06-24 | — | — | US | disclosed |