Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.42 |
| ▸ | TDO2 | P48775 | 3/20 | 0.42 |
| ▸ | SLC18A3 | Q16572 | 6/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7185673 | 1.00 | IDO1 (0.42) | IDO1TDO2SLC18A3CYP2D6HTR6 | |
| SCHEMBL7185676 | 1.00 | IDO1 (0.42) | IDO1TDO2SLC18A3CYP2D6HTR6 | |
| SCHEMBL7185802 | 0.88 | HTR2A (0.35) | IDO1TDO2CYP2D6HTR6 | |
| SCHEMBL7185808 | 0.88 | HTR2A (0.35) | IDO1TDO2CYP2D6HTR6 | |
| SCHEMBL1074094 | 0.77 | HTR2A (0.35) | IDO1TDO2CYP2D6HTR6 | |
| SCHEMBL4854655 | 0.75 | PRCP (0.38) | IDO1TDO2CYP2D6HTR6SIGMAR1 | |
| SCHEMBL7605148 | 0.75 | PRCP (0.38) | IDO1TDO2CYP2D6HTR6SIGMAR1 | |
| SCHEMBL10589173 | 0.75 | PRCP (0.38) | IDO1TDO2CYP2D6HTR6SIGMAR1 | |
| SCHEMBL9808112 | 0.75 | PRCP (0.38) | IDO1TDO2CYP2D6HTR6SIGMAR1 | |
| SCHEMBL3189703 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562921-B1 | Catalyst composition comprising a catalyst precursor compound comprising a metal selected from Groups 4, 5 and 6 of the Periodic Table of Elements and two pi -bonded aromatic ring systems linked by a bridging group, wherein the bridging group | UNIVATION TECHNOLOGIES, LLC | 2003-05-13 | — | — | US | disclosed |