Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7185802 | 1.00 | HTR2A (0.35) | HTR2AHTR6CYP2D6BCHEACHE | |
| SCHEMBL7185673 | 0.88 | IDO1 (0.42) | HTR6CYP2D6IDO1TDO2 | |
| SCHEMBL7185679 | 0.88 | IDO1 (0.42) | HTR6CYP2D6IDO1TDO2 | |
| SCHEMBL7185676 | 0.88 | IDO1 (0.42) | HTR6CYP2D6IDO1TDO2 | |
| SCHEMBL1074094 | 0.84 | HTR2A (0.35) | HTR2AHTR6CYP2D6BCHEACHE | |
| SCHEMBL10589173 | 0.82 | PRCP (0.38) | HTR2AHTR6CYP2D6BCHEACHE | |
| SCHEMBL7605148 | 0.82 | PRCP (0.38) | HTR2AHTR6CYP2D6BCHEACHE | |
| SCHEMBL9808112 | 0.82 | PRCP (0.38) | HTR2AHTR6CYP2D6BCHEACHE | |
| SCHEMBL4854655 | 0.82 | PRCP (0.38) | HTR2AHTR6CYP2D6BCHEACHE | |
| SCHEMBL27636920 | 0.81 | PRCP (0.37) | HTR2AHTR6BCHEACHEIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562921-B1 | Catalyst composition comprising a catalyst precursor compound comprising a metal selected from Groups 4, 5 and 6 of the Periodic Table of Elements and two pi -bonded aromatic ring systems linked by a bridging group, wherein the bridging group | UNIVATION TECHNOLOGIES, LLC | 2003-05-13 | — | — | US | disclosed |