Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 7/20 | 0.35 |
| ▸ | PRCP | P42785 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 6/20 | 0.32 |
| ▸ | HTR2B | P41595 | 6/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4854655 | 0.98 | PRCP (0.38) | HTR2APRCPHTR6IDO1TDO2 | |
| SCHEMBL10589173 | 0.98 | PRCP (0.38) | HTR2APRCPHTR6IDO1TDO2 | |
| SCHEMBL9808112 | 0.98 | PRCP (0.38) | HTR2APRCPHTR6IDO1TDO2 | |
| SCHEMBL7605148 | 0.98 | PRCP (0.38) | HTR2APRCPHTR6IDO1TDO2 | |
| SCHEMBL28839778 | 0.96 | HTR2A (0.35) | HTR2APRCPHTR6IDO1TDO2 | |
| SCHEMBL10352714 | 0.92 | HTR2A (0.38) | HTR2AHTR6HTR2CHTR2BCYP2D6 | |
| SCHEMBL6443438 | 0.84 | HDAC4 (0.34) | KDM4EALDH1A1POLB | |
| SCHEMBL7185802 | 0.84 | HTR2A (0.35) | HTR2AHTR6IDO1TDO2CYP2D6 | |
| SCHEMBL7185808 | 0.84 | HTR2A (0.35) | HTR2AHTR6IDO1TDO2CYP2D6 | |
| SCHEMBL5698322 | 0.80 | HTR2A (0.44) | HTR2AHTR6HTR2CHTR2BCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3187500-B1 | METHOD FOR PRODUCING ANTITUMOR AGENT USING A HOMOGENIZER | EISAI R&D MAN CO LTD (JP) | 2019-01-02 | — | — | EP | disclosed |
| EP-3187500-A1 | METHOD FOR PRODUCING ANTITUMOR AGENT USING HOMOGENIZER | Eisai R&D Management Co., Ltd. (JP) | 2017-07-05 | — | — | EP | disclosed |
| EP-2009041-B1 | Fluorocarbon terminated oligo- and poly-carbonates as surface modifiers | BASF SE (DE) | 2011-05-25 | — | — | EP | disclosed |
| CN-1938345-B | Magnesium chloride-based adducts and catalyst components obtained therefrom | BASELL POLIOLEFINE SRL | 2011-05-18 | — | — | CN | disclosed |
| EP-1846356-B1 | FUNCTIONALIZED ESTERS, AMIDES OR URETHANES OF PERFLUORINATED ALCOHOLS OR AMINES AS SURFACE MODIFIERS | BASF SE (DE) | 2011-01-12 | — | — | EP | disclosed |
| CN-101910180-A | Novel intermediates for halichondrin B analog synthesis and novel desulfonylation reaction for the intermediates | EISAI R&D MAN CO LTD | 2010-12-08 | — | — | CN | disclosed |
| EP-2220094-A1 | NOVEL INTERMEDIATE FOR HALICHONDRIN B ANALOG SYNTHESIS AND NOVEL DESULFONYLATION REACTION USED FOR THE INTERMEDIATE | Eisai R&D Management Co., Ltd. (JP) | 2010-08-25 | — | — | EP | disclosed |
| CN-100548992-C | The 1,2,3-triazoles derivative of microbicidel (for example sterilization) | SYNGENTA PARTICIPATIONS AG (CH) | 2009-10-14 | — | — | CN | disclosed |
| US-20090203771-A1 | NOVEL INTERMEDIATE FOR HALICHONDRIN B ANALOG SYNTHESIS AND NOVEL DESULFONYLATION REACTION USED FOR THE INTERMEDIATE | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-08-13 | — | — | US | disclosed |
| WO-2009064029-A1 | NOVEL INTERMEDIATE FOR HALICHONDRIN B ANALOG SYNTHESIS AND NOVEL DESULFONYLATION REACTION USED FOR THE INTERMEDIATE | EISAI R & D MANAGEMENT CO., LTD. (JP) | 2009-05-22 | — | — | WO | disclosed |
| CN-1938345-A | Magnesium chloride-based adducts and catalyst components obtained therefrom | BASELL POLIOLEFINE SRL (IT) | 2007-03-28 | — | — | CN | disclosed |
| CN-1678593-A | Microbiocidal (e.g. fungicidal) 1,2,3-triazole derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2005-10-05 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203771-A1 | NOVEL INTERMEDIATE FOR HALICHONDRIN B ANALOG SYNTHESIS AND NOVEL DESULFONYLATION REACTION USED FOR THE INTERMEDIATE | NISCH, BMP2, SHH | HTR2A 4252/4885PRCP 1722/4885HTR6 4299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.