Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1A | O00555 | 1/20 | 0.37 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.37 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GALR3 | O60755 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL78348 | 0.90 | CACNA1A (0.41) | CACNA1ACACNA2D1CACNB1ALDH1A1LMNA | |
| SCHEMBL39495 | 0.81 | CA2 (0.50) | ALDH1A1LMNAGAAKDM4EMAPT | |
| SCHEMBL7185815 | 0.80 | HSP90AA1 (0.37) | CACNA1ACACNA2D1CACNB1LMNAIDH1 | |
| SCHEMBL6360901 | 0.77 | CACNA1A (0.39) | CACNA1ACACNA2D1CACNB1ALDH1A1LMNA | |
| SCHEMBL8606475 | 0.76 | GAA (0.44) | CACNA1ACACNA2D1CACNB1ALDH1A1GAA | |
| SCHEMBL9121994 | 0.72 | CA2 (0.44) | ALDH1A1LMNAGAAKDM4EMAPT | |
| SCHEMBL11702172 | 0.71 | CA2 (0.50) | ALDH1A1LMNAGAAKDM4EMAPT | |
| SCHEMBL8466395 | 0.71 | CYP3A4 (0.45) | ALDH1A1LMNAGAATSHRMEN1 | |
| SCHEMBL284652 | 0.71 | CA2 (0.58) | ALDH1A1LMNAGAAKDM4EMAPT | |
| SCHEMBL7191036 | 0.70 | CACNA1A (0.33) | CACNA1ACACNA2D1CACNB1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6569926-B1 | Mixture containing epoxy compound and imidazolidone compoound | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-05-27 | — | — | US | disclosed |
| US-5719257-A | OBTAINED BY ANIONIC POLYMERIZATION OF DERIVATIVES OF 2,2,6,6-TETRAMETHYL-4-/2,3-EPOXYPROPOXY/PIPERIDINE | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1998-02-17 | — | — | US | disclosed |