Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PADI4 | Q9UM07 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7192689 | 0.90 | KRAS (0.42) | LMNAMAPTGAASMN1; SMN2RAB9A | |
| SCHEMBL7073603 | 0.86 | KDM4E (0.43) | MAOBMAOALMNAMAPTGAA | |
| SCHEMBL7070595 | 0.86 | MAOB (0.40) | PADI4MAOBMAOALMNAMAPT | |
| SCHEMBL7072943 | 0.85 | ALDH1A1 (0.41) | MAOBMAOALMNAMAPTGAA | |
| SCHEMBL7073297 | 0.85 | MAOB (0.43) | MAOBMAOALMNAMAPTGAA | |
| SCHEMBL6905188 | 0.82 | MAPT (0.54) | MAOALMNAMAPTGAASMN1; SMN2 | |
| SCHEMBL7075613 | 0.80 | MAOB (0.42) | MAOBMAOALMNAMAPTSMN1; SMN2 | |
| SCHEMBL7072249 | 0.79 | PADI4 (0.46) | PADI4LMNAMAPTGAASMN1; SMN2 | |
| SCHEMBL7070733 | 0.78 | NQO1 (0.45) | MAOBMAOALMNAMAPTGAA | |
| SCHEMBL7073634 | 0.78 | NQO1 (0.45) | MAOBMAOALMNAMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1212315-B1 | NOVEL CHALCONES | INDENA SPA (IT) | 2003-03-26 | — | — | EP | disclosed |
| EP-1212315-A1 | NOVEL CHALCONES | INDENA S.p.A. (IT) | 2002-06-12 | — | — | EP | disclosed |
| WO-2001017988-A1 | NOVEL CHALCONES | INDENA S.P.A. (IT) | 2001-03-15 | — | — | WO | disclosed |