Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PADI4 | Q9UM07 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | LMNA | P02545 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.42 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7186435 | 0.79 | PADI4 (0.41) | PADI4MAPTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL7070595 | 0.78 | MAOB (0.40) | PADI4MAPTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL8876628 | 0.78 | ALDH1A1 (0.52) | MAPTLMNAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL7073031 | 0.78 | ALDH1A1 (0.52) | MAPTLMNAALDH1A1SMN1; SMN2GAA | |
| SCHEMBL7072943 | 0.78 | ALDH1A1 (0.41) | MAPTLMNAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL7073297 | 0.78 | MAOB (0.43) | MAPTLMNAALDH1A1SMN1; SMN2GAA | |
| SCHEMBL7192689 | 0.77 | KRAS (0.42) | MAPTLMNAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL7072948 | 0.76 | KRAS (0.43) | MAPTLMNAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL7075613 | 0.76 | MAOB (0.42) | MAPTLMNAALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL7070128 | 0.76 | KRAS (0.42) | MAPTLMNAALDH1A1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6620842-B2 | Chalcones | INDENA SPA (IT) | 2003-09-16 | — | — | US | disclosed |
| EP-1212315-B1 | NOVEL CHALCONES | INDENA SPA (IT) | 2003-03-26 | — | — | EP | disclosed |
| US-20030055056-A1 | For use as antitumor and immune suppressive agents, as inhibitors of proliferative cell growth and as prophylactic agents to inhibit and prevent cancer and non-malignant cell growth | INDENA S.P.A. (IT) | 2003-03-20 | — | — | US | disclosed |
| EP-1212315-A1 | NOVEL CHALCONES | INDENA S.p.A. (IT) | 2002-06-12 | — | — | EP | disclosed |
| WO-2001017988-A1 | NOVEL CHALCONES | INDENA S.P.A. (IT) | 2001-03-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030055056-A1 | For use as antitumor and immune suppressive agents, as inhibitors of proliferative cell growth and as prophylactic agents to inhibit and prevent cancer and non-malignant cell growth | HDGF, MKI67, HPD | PADI4 1510/4885MAPT 4477/4885LMNA 4635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.