Sugi Predict

Sugi Predict / Compounds / SCHEMBL7186470

SCHEMBL7186470

SCHEMBL7186470

COc1cccc(OC)c1C(=O)[P](=O)c1ccccc1C(=O)c1c(Cl)cccc1Cl

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RORC P51449 2/20 0.42
▸ KMT2A Q03164 1/20 0.42
▸ LMNA P02545 3/20 0.41
▸ HPGD P15428 1/20 0.40
▸ RAB9A P51151 1/20 0.40
▸ SMN1; SMN2 Q16637 1/20 0.40
▸ L3MBTL1 Q9Y468 1/20 0.40
▸ CA12 O43570 1/20 0.40
▸ CA1 P00915 1/20 0.40
▸ CA2 P00918 1/20 0.40
▸ CA7 P43166 1/20 0.40
▸ CA9 Q16790 1/20 0.40
▸ CA14 Q9ULX7 1/20 0.40
▸ FABP4 P15090 1/20 0.39
▸ ALDH1A1 P00352 1/20 0.39
▸ GAA P10253 1/20 0.39
▸ CES2 O00748 1/20 0.39
▸ CES1 P23141 1/20 0.39
▸ MAPK14 Q16539 2/20 0.37
▸ MAPK13 O15264 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7177554 0.91 LMNA (0.39) RORCKMT2ALMNARAB9ACA12
SCHEMBL7175462 0.91 KMT2A (0.45) RORCKMT2ALMNASMN1; SMN2ALDH1A1
SCHEMBL7174638 0.91 HPGD (0.38) RORCKMT2ALMNAHPGDRAB9A
SCHEMBL7189134 0.90 CA12 (0.40) RORCKMT2ALMNAHPGDRAB9A
SCHEMBL7180809 0.89 LMNA (0.39) RORCKMT2ALMNAHPGDRAB9A
SCHEMBL7186774 0.88 KMT2A (0.39) RORCKMT2ALMNAHPGDRAB9A
SCHEMBL7182106 0.86 KMT2A (0.45) KMT2ALMNASMN1; SMN2ALDH1A1GAA
SCHEMBL7183272 0.86 CA12 (0.41) RORCKMT2ARAB9ACA12CA1
SCHEMBL7177390 0.86 CA12 (0.41) KMT2ALMNARAB9ACA12CA1
SCHEMBL7176979 0.85 CA12 (0.40) KMT2AHPGDRAB9ASMN1; SMN2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6579663-B2 Chemical intermediates such as lithium 2,6-dimethylbenzoyl phenylphosphine for preparation of acylphosphines, acylphosphine oxides or acylphosphine sulfides CIBA SPECIALTY CHEMICALS CORPORATION 2003-06-17 — — US disclosed
US-20020107413-A1 Organometallic monoacylarylphosphines WOLF JEAN-PIERRE (CH) 2002-08-08 — — US disclosed
US-6399805-B2 SUCH AS LITHIUM 2,6-DIMETHYLBENZOYLPHENYLPHOSPHINE, USE AS PHOTOINITIATORS IN PHOTOCURABLE COMPOSITIONS SUCH AS FOR PHOTOGRAPHIC PRODUCTION OF RELIEF IMAGES CIBA SPECIALTY CHEMICALS CORPORATION 2002-06-04 — — US disclosed
US-20010031898-A1 Organometallic monoacylarylphosphines CIBA SPECIALTY CHEMICALS CORP. 2001-10-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020107413-A1 Organometallic monoacylarylphosphines CBR1, NAF1, DHCR24 RORC 1336/4885KMT2A 1586/4885LMNA 3241/4885
US-20010031898-A1 Organometallic monoacylarylphosphines NAF1, DHCR24, CBR1 RORC 1254/4885KMT2A 956/4885LMNA 3247/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.