SCHEMBL7186481

SCHEMBL7186481

O=C(Pc1ccccc1)c1c(COc2ccccc2)cccc1COc1ccccc1.[LiH]

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 13/20 0.48
FFAR4 Q5NUL3 9/20 0.48
AKR1B1 P15121 1/20 0.47
PTGER1 P34995 1/20 0.47
PTGER4 P35408 1/20 0.47
PTGER3 P43115 1/20 0.47
PTGER2 P43116 1/20 0.47
KDM4E B2RXH2 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
PTPRC P08575 1/20 0.46
PTPN1 P18031 1/20 0.46
NR4A2 P43354 2/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7182613 0.82 GABRA1 (0.42) FFAR1
SCHEMBL5994572 0.78 PTGER1 (0.47) FFAR1FFAR4AKR1B1PTGER1PTGER4
SCHEMBL7189087 0.76 PTGS1 (0.51) FFAR1FFAR4NR4A2
SCHEMBL5995941 0.75 PTGER4 (0.44) FFAR1FFAR4PTGER1PTGER4PTGER3
SCHEMBL7185160 0.75 FFAR1 (0.50) FFAR1FFAR4NR4A2
Oxalic Acid SCHEMBL7593690 0.74 PTPRC (0.70) FFAR1FFAR4PTGER1PTGER4PTGER3
SCHEMBL5997202 0.74 PTGER4 (0.43) FFAR1FFAR4PTGER1PTGER4PTGER3
SCHEMBL5996822 0.74 PTGER1 (0.43) FFAR1FFAR4PTGER1PTGER4PTGER3
SCHEMBL5997090 0.74 PTPRC (0.46) FFAR1FFAR4PTGER1PTGER4PTGER3
SCHEMBL7177198 0.73 L3MBTL1 (0.56) FFAR1FFAR4SMN1; SMN2NR4A2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6579663-B2 Chemical intermediates such as lithium 2,6-dimethylbenzoyl phenylphosphine for preparation of acylphosphines, acylphosphine oxides or acylphosphine sulfides CIBA SPECIALTY CHEMICALS CORPORATION 2003-06-17 US disclosed
US-20020107413-A1 Organometallic monoacylarylphosphines WOLF JEAN-PIERRE (CH) 2002-08-08 US disclosed
US-6399805-B2 SUCH AS LITHIUM 2,6-DIMETHYLBENZOYLPHENYLPHOSPHINE, USE AS PHOTOINITIATORS IN PHOTOCURABLE COMPOSITIONS SUCH AS FOR PHOTOGRAPHIC PRODUCTION OF RELIEF IMAGES CIBA SPECIALTY CHEMICALS CORPORATION 2002-06-04 US disclosed
US-20010031898-A1 Organometallic monoacylarylphosphines CIBA SPECIALTY CHEMICALS CORP. 2001-10-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020107413-A1 Organometallic monoacylarylphosphines CBR1, NAF1, DHCR24 FFAR1 671/4885FFAR4 1611/4885AKR1B1 700/4885
US-20010031898-A1 Organometallic monoacylarylphosphines NAF1, DHCR24, CBR1 FFAR1 711/4885FFAR4 1526/4885AKR1B1 747/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.