Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 1/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 8/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | HSD3B2 | P26439 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
| ▸ | KIF11 | P52732 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4631267 | 0.88 | TACR2 (0.62) | TACR2CYP3A4CNR1TSHR | |
| SCHEMBL4800783 | 0.83 | MEN1 (0.47) | TACR2CYP2C19NPC1MEN1KMT2A | |
| SCHEMBL4631280 | 0.82 | TACR2 (0.49) | TACR2CYP2C9CYP3A4CYP2C19TSHR | |
| SCHEMBL7174179 | 0.78 | TACR2 (0.43) | TACR2KMT2A | |
| SCHEMBL7180636 | 0.78 | TACR2 (0.43) | TACR2KMT2A | |
| SCHEMBL27394574 | 0.78 | TACR2 (0.42) | TACR2HSD11B1CYP2C9CYP3A4CYP2C19 | |
| Hydrochloric Acid SCHEMBL4802792 | 0.77 | TACR2 (0.42) | TACR2KMT2A | |
| Hydrochloric Acid SCHEMBL4800620 | 0.77 | TACR2 (0.42) | TACR2KMT2A | |
| SCHEMBL4630858 | 0.76 | TACR2 (0.43) | TACR2 | |
| SCHEMBL2294993 | 0.75 | HSD11B1 (0.39) | TACR2HSD11B1CNR1NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200417-B1 | METHOD FOR PREPARING 2-(2-ARYLMORPHOLIN-2-YL)ETHANOL DERIVATIVES AND INTERMEDIATES | SANOFI SYNTHELABO (FR) | 2003-10-22 | — | — | EP | disclosed |
| EP-1200417-A1 | METHOD FOR PREPARING 2-(2-ARYLMORPHOLIN-2-YL)ETHANOL DERIVATIVES AND INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001004105-A1 | METHOD FOR PREPARING 2-(2-ARYLMORPHOLIN-2-YL)ETHANOL DERIVATIVES AND INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2001-01-18 | — | — | WO | disclosed |