Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.43 |
| ▸ | PPARG | P37231 | 7/20 | 0.43 |
| ▸ | PPARD | Q03181 | 7/20 | 0.43 |
| ▸ | PPARA | Q07869 | 7/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.43 |
| ▸ | TLR2 | O60603 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | FABP4 | P15090 | 2/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6202483 | 1.00 | ADRA1A (0.50) | ADRA1APRMT1TSHRLMNANFKB1 | |
| SCHEMBL7289421 | 1.00 | ADRA1A (0.50) | ADRA1APRMT1TSHRLMNANFKB1 | |
| SCHEMBL7286381 | 0.98 | ADRA1A (0.47) | ADRA1APRMT1TSHRLMNANFKB1 | |
| SCHEMBL7286124 | 0.92 | TSHR (0.43) | ADRA1APRMT1TSHRLMNANFKB1 | |
| SCHEMBL13290730 | 0.78 | ADRA1A (0.55) | ADRA1APRMT1TSHRLMNANFKB1 | |
| SCHEMBL9614821 | 0.78 | POLB (0.30) | — | |
| Azelaic Acid SCHEMBL27377315 | 0.74 | TSHR (0.60) | TSHRLMNANFKB1PMP22ALDH1A1 | |
| Azelaic Acid SCHEMBL27659344 | 0.74 | TSHR (0.60) | TSHRLMNANFKB1PMP22ALDH1A1 | |
| SCHEMBL28284450 | 0.74 | ADRA1A (0.52) | ADRA1APRMT1TSHRLMNANFKB1 | |
| SCHEMBL16487196 | 0.74 | TDP1 (0.69) | ADRA1APRMT1TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6566330-B1 | As chemical intermediate | MEDICAL UNIVERSITY OF SOUTH CAROLINA FOUNDATION RESEARCH DEVELOPMENT | 2003-05-20 | — | — | US | disclosed |
| US-20020137730-A1 | Positively charged non-natural amino acids, methods of making and using thereof in peptides | MEDICAL UNIVERSITY OF SOUTH CAROLINA | 2002-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020137730-A1 | Positively charged non-natural amino acids, methods of making and using thereof in peptides | NGLY1, LNPEP, DNPEP | ADRA1A 4773/4885PRMT1 420/4885TSHR 3728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.