Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 8/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 8/20 | 0.43 |
| ▸ | TAS1R2 | Q8TE23 | 6/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | FABP3 | P05413 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.35 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.35 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7183280 | 0.96 | ALDH1A1 (0.50) | ALDH1A1KDM4EHSD17B10TAS1R3TAS1R1 | |
| SCHEMBL7189534 | 0.93 | ALDH1A1 (0.45) | ALDH1A1KDM4EHSD17B10TAS1R3TAS1R1 | |
| SCHEMBL7187679 | 0.92 | ALDH1A1 (0.54) | ALDH1A1KDM4EHSD17B10TAS1R3TAS1R1 | |
| SCHEMBL7189336 | 0.91 | TAS1R3 (0.43) | ALDH1A1KDM4EHSD17B10TAS1R3TAS1R1 | |
| SCHEMBL7175812 | 0.89 | TAS1R3 (0.41) | ALDH1A1KDM4EHSD17B10TAS1R3TAS1R1 | |
| SCHEMBL7178072 | 0.88 | ALDH1A1 (0.43) | ALDH1A1KDM4EHSD17B10TAS1R3TAS1R1 | |
| SCHEMBL7181188 | 0.88 | ALDH1A1 (0.49) | ALDH1A1KDM4EHSD17B10TAS1R3TAS1R1 | |
| SCHEMBL7175298 | 0.87 | TOP1 (0.40) | ALDH1A1KDM4EHSD17B10TAS1R3TAS1R1 | |
| SCHEMBL7182453 | 0.87 | TYK2 (0.44) | ALDH1A1TYK2ABL1SRCTRPM4 | |
| SCHEMBL7179862 | 0.87 | TYK2 (0.44) | ALDH1A1TYK2ABL1SRCTRPM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6579663-B2 | Chemical intermediates such as lithium 2,6-dimethylbenzoyl phenylphosphine for preparation of acylphosphines, acylphosphine oxides or acylphosphine sulfides | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-06-17 | — | — | US | disclosed |
| US-20020107413-A1 | Organometallic monoacylarylphosphines | WOLF JEAN-PIERRE (CH) | 2002-08-08 | — | — | US | disclosed |
| US-6399805-B2 | SUCH AS LITHIUM 2,6-DIMETHYLBENZOYLPHENYLPHOSPHINE, USE AS PHOTOINITIATORS IN PHOTOCURABLE COMPOSITIONS SUCH AS FOR PHOTOGRAPHIC PRODUCTION OF RELIEF IMAGES | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-06-04 | — | — | US | disclosed |
| US-20010031898-A1 | Organometallic monoacylarylphosphines | CIBA SPECIALTY CHEMICALS CORP. | 2001-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020107413-A1 | Organometallic monoacylarylphosphines | CBR1, NAF1, DHCR24 | ALDH1A1 3416/4885KDM4E 3226/4885HSD17B10 56/4885 |
| US-20010031898-A1 | Organometallic monoacylarylphosphines | NAF1, DHCR24, CBR1 | ALDH1A1 3984/4885KDM4E 2651/4885HSD17B10 42/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.