Sugi Predict

Sugi Predict / Compounds / SCHEMBL7186797

SCHEMBL7186797

SCHEMBL7186797

Cc1cccc(Cl)c1C(=O)P(=O)(C(=O)c1c(C(C)(C)C)cc(C(C)(C)C)cc1C(C)(C)C)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RAB9A P51151 3/20 0.39
▸ NPSR1 Q6W5P4 2/20 0.39
▸ GAA P10253 2/20 0.39
▸ MAPT P10636 1/20 0.39
▸ ITGB1 P05556 4/20 0.36
▸ ITGA4 P13612 4/20 0.36
▸ ITGA2 P17301 1/20 0.36
▸ ITGB7 P26010 1/20 0.36
▸ TYK2 P29597 1/20 0.36
▸ NPC1 O15118 1/20 0.34
▸ ALDH1A1 P00352 1/20 0.34
▸ GLA P06280 1/20 0.34
▸ ATM Q13315 1/20 0.34
▸ L3MBTL1 Q9Y468 1/20 0.34
▸ PTGS2 P35354 2/20 0.34
▸ KMT2A Q03164 2/20 0.34
▸ MEN1 O00255 1/20 0.34
▸ FABP3 P05413 1/20 0.34
▸ FABP4 P15090 1/20 0.34
▸ ABL1 P00519 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7182622 0.93 NPSR1 (0.41) RAB9ANPSR1GAAMAPTITGB1
SCHEMBL7175714 0.92 GAA (0.41) RAB9ANPSR1GAAMAPTITGB1
SCHEMBL7181473 0.92 NPSR1 (0.39) NPSR1GAAALDH1A1PTGS2KMT2A
SCHEMBL7175328 0.87 MAPT (0.42) RAB9ANPSR1GAAMAPTTYK2
SCHEMBL7183900 0.86 MEN1 (0.39) NPSR1GAAMAPTALDH1A1L3MBTL1
SCHEMBL7177661 0.85 FABP4 (0.37) RAB9ANPSR1GAAMAPTITGB1
SCHEMBL7182360 0.84 TP53 (0.39) NPSR1GAAMAPTALDH1A1L3MBTL1
SCHEMBL7182453 0.84 TYK2 (0.44) GAAMAPTITGB1ITGA4ITGA2
SCHEMBL7179862 0.84 TYK2 (0.44) GAAMAPTITGB1ITGA4ITGA2
SCHEMBL7189845 0.83 LMNA (0.37) NPSR1GAAL3MBTL1PTGS2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6579663-B2 Chemical intermediates such as lithium 2,6-dimethylbenzoyl phenylphosphine for preparation of acylphosphines, acylphosphine oxides or acylphosphine sulfides CIBA SPECIALTY CHEMICALS CORPORATION 2003-06-17 — — US disclosed
US-20020107413-A1 Organometallic monoacylarylphosphines WOLF JEAN-PIERRE (CH) 2002-08-08 — — US disclosed
US-6399805-B2 SUCH AS LITHIUM 2,6-DIMETHYLBENZOYLPHENYLPHOSPHINE, USE AS PHOTOINITIATORS IN PHOTOCURABLE COMPOSITIONS SUCH AS FOR PHOTOGRAPHIC PRODUCTION OF RELIEF IMAGES CIBA SPECIALTY CHEMICALS CORPORATION 2002-06-04 — — US disclosed
US-20010031898-A1 Organometallic monoacylarylphosphines CIBA SPECIALTY CHEMICALS CORP. 2001-10-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020107413-A1 Organometallic monoacylarylphosphines CBR1, NAF1, DHCR24 RAB9A 1818/4885NPSR1 2669/4885GAA 4753/4885
US-20010031898-A1 Organometallic monoacylarylphosphines NAF1, DHCR24, CBR1 RAB9A 2155/4885NPSR1 3007/4885GAA 4793/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.