Gamma Oryzanol

Gamma Oryzanol

SCHEMBL718726

COc1cc(/C=C/C(=O)O[C@H]2CC[C@]34C[C@]35CC[C@]3(C)[C@@H]([C@H](C)CCC=C(C)C)CC[C@@]3(C)[C@@H]5CC[C@H]4C2(C)C)ccc1O

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.60
▸ KMT2A Q03164 1/20 0.60
▸ ACLY P53396 2/20 0.50
▸ ACACA Q13085 2/20 0.50
▸ RELA Q04206 1/20 0.49
▸ MAPT P10636 3/20 0.48
▸ KDM4E B2RXH2 2/20 0.48
▸ GAA P10253 2/20 0.48
▸ XBP1 P17861 1/20 0.48
▸ NPSR1 Q6W5P4 1/20 0.48
▸ SLC10A1 Q14973 1/20 0.43
▸ ALDH1A1 P00352 2/20 0.42
▸ USP2 O75604 1/20 0.42
▸ CYP3A4 P08684 1/20 0.42
▸ ALOX15 P16050 1/20 0.42
▸ PTPN1 P18031 1/20 0.41
▸ PTGS1 P23219 1/20 0.39
▸ PTGS2 P35354 1/20 0.39
▸ PTPN11 Q06124 1/20 0.39
▸ ELANE P08246 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Gamma Oryzanol SCHEMBL23105398 1.00 MEN1 (0.60) MEN1KMT2AACLYACACARELA
Gamma Oryzanol SCHEMBL29357024 1.00 MEN1 (0.60) MEN1KMT2AACLYACACARELA
Gamma Oryzanol SCHEMBL21235210 1.00 MEN1 (0.60) MEN1KMT2AACLYACACARELA
Gamma Oryzanol SCHEMBL12152368 1.00 MEN1 (0.60) MEN1KMT2AACLYACACARELA
Gamma Oryzanol SCHEMBL29354302 1.00 MEN1 (0.60) MEN1KMT2AACLYACACARELA
SCHEMBL10049046 0.94 MEN1 (0.53) MEN1KMT2AACLYACACARELA
SCHEMBL31149054 0.94 ACLY (0.52) MEN1KMT2AACLYACACARELA
SCHEMBL10017450 0.90 MEN1 (0.51) MEN1KMT2AACLYACACARELA
SCHEMBL12152371 0.90 MEN1 (0.63) MEN1KMT2AACLYACACARELA
SCHEMBL29524845 0.90 MEN1 (0.63) MEN1KMT2AACLYACACARELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 413 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12385071-B2 Methods for the production of ferulic acid INVENTURE RENEWABLES, INC. (US) 2025-08-12 — — US claimed
US-12342841-B2 Compositions for improving low testosterone levels CYTOSOLVE, INC. (US) 2025-07-01 — — US claimed
CN-119894520-A External skin preparation composition 志瑞亚新药工业株式会社 2025-04-25 — — CN claimed
EP-4539853-A1 HUMORAL IMMUNE ACTIVATORS FOR THE TREATMENT OF HUMORAL IMMUNOSUPPRESSED PATHOLOGIES, CANCER AND INFECTIOUS DISEASE AND HUMORAL IMMUNE SUPPRESSORS FOR THE TREATMENT OF INFLAMMATORY DISEASES Navrogen, Inc. (US) 2025-04-23 — — EP claimed
WO-2025063229-A1 SKIN-IMPROVING AGENT 第一三共ヘルスケア株式会社 2025-03-27 — — WO claimed
WO-2025063228-A1 SKIN-IMPROVING AGENT 第一三共ヘルスケア株式会社 2025-03-27 — — WO claimed
CN-119677519-A Humoral immune activators for the treatment of humoral immune-suppressive pathologies, cancers and infectious diseases and humoral immune inhibitors for the treatment of inflammatory diseases 纳夫罗根公司 2025-03-21 — — CN claimed
WO-2025048425-A1 COMPOSITION FOR ALLEVIATING SKIN PIGMENTATION 주식회사 엘지생활건강 2025-03-06 — — WO claimed
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 — — US claimed
EP-4404969-A1 EXPANSION PROCESSES AND AGENTS FOR TUMOR INFILTRATING LYMPHOCYTES Iovance Biotherapeutics, Inc. (US) 2024-07-31 — — EP claimed
EP-4149438-A1 SOLID ORAL COMPOSITIONS COMPRISING COMPOSITE MONOLITHIC MATRICES FOR CHRONOTROPIC ADMINISTRATION OF ACTIVE INGREDIENTS IN THE GASTROINTESTINAL TRACT Mogon Pharmaceuticals Sagl (CH) 2023-03-22 — — EP claimed
US-20230027119-A1 METHODS FOR THE PRODUCTION OF FERULIC ACID INVENTURE RENEWABLES INC (US) 2023-01-26 — — US claimed
CN-111620775-B Method for preparing cycloartenyl ferulate by selectively hydrolyzing oryzanol 浙江得乐康食品股份有限公司 2023-01-10 — — CN claimed
WO-2022203145-A1 LIPID NANOPARTICLE COMPOSITION PREPARED USING MASTIC GUM OR GAMMA ORYZANOL 주식회사 앱스바이오 2022-09-29 — — WO claimed
WO-2022182527-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2022-09-01 — — WO claimed
US-20220273690-A1 Edible Formulations Based on Active Ingredients and Arginine GRAAL S R L (IT) 2022-09-01 — — US claimed
EP-4021508-A1 FORMULATIONS COMPRISING ARGININE AND/OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF AND AN ACID ACTIVE INGREDIENT WITH A PKA OF 1 -5 Graal S.r.l. (IT) 2022-07-06 — — EP claimed
US-20220117284-A1 Compositions for Improving Low Testosterone Levels CYTOSOLVE, INC. 2022-04-21 — — US claimed
EP-3508471-B1 METHOD FOR PRODUCING MICROPARTICLES FROM PRESSURIZED AND HEATED STARTING MATERIAL SOLUTION M TECHNIQUE CO LTD (JP) 2022-04-20 — — EP claimed
WO-2022036435-A1 UNDERWEAR FOR DISPENSING THERAPEUTIC SUBSTANCES SCOTT HILARY BRENDA (CA) 2022-02-24 — — WO claimed
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