Gamma Oryzanol

Gamma Oryzanol

SCHEMBL29357024

COc1cc(/C=C/C(=O)O[C@H]2CC[C@]34C[C@]35CC[C@]3(C)[C@@H](C(C)CCC=C(C)C)CC[C@@]3(C)C5CCC4C2(C)C)ccc1O

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.60
▸ KMT2A Q03164 1/20 0.60
▸ ACLY P53396 2/20 0.50
▸ ACACA Q13085 2/20 0.50
▸ RELA Q04206 1/20 0.49
▸ MAPT P10636 3/20 0.48
▸ KDM4E B2RXH2 2/20 0.48
▸ GAA P10253 2/20 0.48
▸ XBP1 P17861 1/20 0.48
▸ NPSR1 Q6W5P4 1/20 0.48
▸ SLC10A1 Q14973 1/20 0.43
▸ ALDH1A1 P00352 2/20 0.42
▸ USP2 O75604 1/20 0.42
▸ CYP3A4 P08684 1/20 0.42
▸ ALOX15 P16050 1/20 0.42
▸ PTPN1 P18031 1/20 0.41
▸ PTGS1 P23219 1/20 0.39
▸ PTGS2 P35354 1/20 0.39
▸ PTPN11 Q06124 1/20 0.39
▸ ELANE P08246 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Gamma Oryzanol SCHEMBL23105398 1.00 MEN1 (0.60) MEN1KMT2AACLYACACARELA
Gamma Oryzanol SCHEMBL21235210 1.00 MEN1 (0.60) MEN1KMT2AACLYACACARELA
Gamma Oryzanol SCHEMBL12152368 1.00 MEN1 (0.60) MEN1KMT2AACLYACACARELA
Gamma Oryzanol SCHEMBL29354302 1.00 MEN1 (0.60) MEN1KMT2AACLYACACARELA
Gamma Oryzanol SCHEMBL718726 1.00 MEN1 (0.60) MEN1KMT2AACLYACACARELA
SCHEMBL10049046 0.94 MEN1 (0.53) MEN1KMT2AACLYACACARELA
SCHEMBL31149054 0.94 ACLY (0.52) MEN1KMT2AACLYACACARELA
SCHEMBL10017450 0.90 MEN1 (0.51) MEN1KMT2AACLYACACARELA
SCHEMBL12152371 0.90 MEN1 (0.63) MEN1KMT2AACLYACACARELA
SCHEMBL29524845 0.90 MEN1 (0.63) MEN1KMT2AACLYACACARELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023175391-A1 EMULSIONS AS OXIDATION PROTECTANTS FOR CONVENTIONAL FRYING OILS IN FOOD APPLICATIONS ALIANZA TEAM INTERNATIONAL S.A. (CO) 2023-09-21 — — WO claimed
CN-115537062-A 3D printing ink material, preparation method thereof and bracket-free invisible appliance with shape memory function 烟台先进材料与绿色制造山东省实验室 2022-12-30 — — CN claimed
US-12414977-B2 Method of administering seaberry and saw palmetto extracts to inhibit 5α-reductase activity ORYZA OIL & FAT CHEMICAL CO., LTD. (JP) 2025-09-16 — — US disclosed
US-20250268972-A1 5a-REDUCTASE INHIBITOR ORYZA OIL & FAT CHEMICAL CO., LTD. (JP) 2025-08-28 — — US disclosed
WO-2025048546-A1 COMPOSITION FOR IMPROVING SKIN CONDITION 주식회사 엘지생활건강 2025-03-06 — — WO disclosed
EP-4510992-A2 SKIN BARRIER PROTECTIVE DELIVERY SYSTEMS AND METHODS THEREOF Bobo Labs Inc. (US) 2025-02-26 — — EP disclosed
CN-119343126-A Skin barrier protection delivery system and method thereof 宝宝实验室公司 2025-01-21 — — CN disclosed
US-20250017830-A1 SKIN BARRIER PROTECTIVE DELIVERY SYSTEMS AND METHODS THEREOF BOBO LABS INC. (US) 2025-01-16 — — US disclosed
US-12121603-B1 Skin barrier protective delivery systems BOBO LABS INC. (US) 2024-10-22 — — US disclosed
WO-2024205344-A1 COSMETIC COMPOSITION FOR AMELIORATING SKIN AGING 주식회사 엘지생활건강 2024-10-03 — — WO disclosed
US-20240325265-A1 SKIN BARRIER PROTECTIVE DELIVERY SYSTEMS AND METHODS THEREOF BOBO LABS INC. 2024-10-03 — — US disclosed
WO-2022170114-A1 SKINCARE COMPOSITIONS AND METHODS OF USE THEREOF MODERN MEADOW, INC. (US) 2022-08-11 — — WO disclosed
CN-114656590-A Degradable thermosetting 3D printing mold and preparation method thereof 中国科学院福建物质结构研究所 2022-06-24 — — CN disclosed
CN-114591601-A Preparation method of multifunctional 4D printing material 中国科学院福建物质结构研究所 2022-06-07 — — CN disclosed
WO-2022092284-A1 COMPOSITION CONTAINING LIPID PEPTIDE AND SUCROSE ESTER 日産化学株式会社 2022-05-05 — — WO disclosed
EP-3558236-B1 LIQUID PERSONAL CLEANSING COMPOSITION UNILEVER IP HOLDINGS B V (NL) 2022-04-13 — — EP disclosed
CN-110381916-B Liquid personal cleansing compositions 联合利华知识产权控股有限公司 2022-04-08 — — CN disclosed
US-20220062121-A1 MICROEMULSION COMPOSITION, CURED MATERIAL THEREOF, AND COSMETIC CONTAINING THE CURED MATERIAL SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-03-03 — — US disclosed
CN-112111038-B Water-soluble photosensitive resin and preparation method and application thereof 中国科学院福建物质结构研究所 2022-02-18 — — CN disclosed
EP-3222269-B1 HAIR PAPILLA CELL ACTIVATOR EZAKI GLICO CO (JP) 2022-01-26 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220062121-A1 MICROEMULSION COMPOSITION, CURED MATERIAL THEREOF, AND COSMETIC CONTAINING THE CURED MATERIAL MGLL, LIPA, MAN2B1 MEN1 320/4885KMT2A 1856/4885ACLY 2409/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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