Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 11/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 10/20 | 0.47 |
| ▸ | ME2 | P23368 | 1/20 | 0.39 |
| ▸ | ME1 | P48163 | 1/20 | 0.39 |
| ▸ | ME3 | Q16798 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7193824 | 0.92 | ESR1 (0.47) | ESR1ESR2TDP1ALDH1A1 | |
| SCHEMBL7189203 | 0.91 | ESR1 (0.47) | ESR1ESR2TDP1ALDH1A1P2RY10 | |
| SCHEMBL7195102 | 0.91 | CYP4F2 (0.46) | ESR1ESR2ALDH1A1 | |
| SCHEMBL7195079 | 0.88 | ESR1 (0.49) | ESR1ESR2P2RY10 | |
| SCHEMBL7186036 | 0.84 | ESR1 (0.49) | ESR1ESR2 | |
| SCHEMBL7190482 | 0.84 | ESR1 (0.53) | ESR1 | |
| SCHEMBL7195351 | 0.83 | MAPT (0.47) | ESR1ESR2TDP1ALDH1A1 | |
| SCHEMBL7189822 | 0.83 | ESR1 (0.52) | ESR1ESR2 | |
| SCHEMBL7190060 | 0.82 | ESR1 (0.40) | ESR1ESR2APP | |
| SCHEMBL7193207 | 0.81 | ESR1 (0.49) | ESR1ESR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835867-B1 | 1-Aryloxy-2-arylnaphthyl compounds, intermediates, compositions, and methods | LILLY CO ELI (US) | 2003-12-03 | — | — | EP | claimed |