Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 15/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.53 |
| ▸ | PCNA | P12004 | 1/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 12/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7189113 | 0.93 | FFAR1 (0.57) | FFAR1AKR1B1FFAR4SRD5A2 | |
| SCHEMBL7187264 | 0.90 | FFAR1 (0.56) | FFAR1AKR1B1FFAR4SRD5A2 | |
| SCHEMBL7188049 | 0.90 | FFAR1 (0.56) | FFAR1AKR1B1FFAR4SRD5A2 | |
| SCHEMBL7187252 | 0.89 | ESR1 (0.62) | ESR1FFAR1PCNAFFAR4 | |
| SCHEMBL7190740 | 0.88 | FFAR1 (0.53) | ESR1FFAR1AKR1B1FFAR4 | |
| SCHEMBL7195102 | 0.86 | CYP4F2 (0.46) | ESR1FFAR1AKR1B1FFAR4 | |
| SCHEMBL7190060 | 0.85 | ESR1 (0.40) | ESR1FFAR1AKR1B1FFAR4 | |
| SCHEMBL7187874 | 0.85 | ESR1 (0.55) | ESR1FFAR1PCNAFFAR4 | |
| SCHEMBL7187512 | 0.84 | ESR1 (0.47) | ESR1 | |
| SCHEMBL7188059 | 0.83 | ESR1 (0.55) | ESR1FFAR1PCNAFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835867-B1 | 1-Aryloxy-2-arylnaphthyl compounds, intermediates, compositions, and methods | LILLY CO ELI (US) | 2003-12-03 | — | — | EP | claimed |
| US-5916916-A | USEFUL AS SELECTIVE ESTROGEN RECEPTOR MODULATORS. | ELI LILLY AND COMPANY (US) | 1999-06-29 | — | — | US | claimed |
| EP-0835867-A1 | 1-Aryloxy-2-arylnaphthyl compounds, intermediates, compositions, and methods | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | claimed |
| EP-0835867-B1 | 1-Aryloxy-2-arylnaphthyl compounds, intermediates, compositions, and methods | LILLY CO ELI (US) | 2003-12-03 | — | — | EP | disclosed |
| US-5916916-A | USEFUL AS SELECTIVE ESTROGEN RECEPTOR MODULATORS. | ELI LILLY AND COMPANY (US) | 1999-06-29 | — | — | US | disclosed |
| EP-0835867-A1 | 1-Aryloxy-2-arylnaphthyl compounds, intermediates, compositions, and methods | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |