Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 7/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7187431 | 0.92 | MMP3 (0.43) | ESR1ESR2FFAR1FFAR4APP | |
| SCHEMBL7195102 | 0.87 | CYP4F2 (0.46) | ESR1ESR2FFAR1FFAR4AKR1B1 | |
| SCHEMBL7190482 | 0.85 | ESR1 (0.53) | ESR1FFAR1FFAR4AKR1B1 | |
| SCHEMBL7187512 | 0.82 | ESR1 (0.47) | ESR1ESR2APP | |
| SCHEMBL7182817 | 0.79 | ESR1 (0.51) | ESR1ESR2LTB4R2NPC1 | |
| SCHEMBL7195351 | 0.79 | MAPT (0.47) | ESR1ESR2FFAR1FFAR4NPC1 | |
| SCHEMBL7189113 | 0.78 | FFAR1 (0.57) | FFAR1FFAR4AKR1B1 | |
| SCHEMBL7188049 | 0.78 | FFAR1 (0.56) | FFAR1FFAR4AKR1B1NPC1RAB9A | |
| SCHEMBL8501206 | 0.78 | MAPT (0.45) | ESR1ESR2NPC1RAB9A | |
| SCHEMBL7193207 | 0.77 | ESR1 (0.49) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835867-B1 | 1-Aryloxy-2-arylnaphthyl compounds, intermediates, compositions, and methods | LILLY CO ELI (US) | 2003-12-03 | — | — | EP | claimed |