Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.88 |
| ▸ | MMP2 | P08253 | 2/20 | 0.88 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.88 |
| ▸ | COMT | P21964 | 1/20 | 0.88 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.88 |
| ▸ | METAP2 | P50579 | 1/20 | 0.88 |
| ▸ | METAP1 | P53582 | 1/20 | 0.88 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.88 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.79 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.79 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | GMNN | O75496 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxyquinoline SCHEMBL29716519 | 0.94 | TSHR (1.00) | TSHRMMP2CHRM1COMTADRA1A | |
| Oxyquinoline SCHEMBL37189 | 0.94 | TSHR (1.00) | TSHRMMP2CHRM1COMTADRA1A | |
| Oxyquinoline SCHEMBL29365411 | 0.94 | TSHR (1.00) | TSHRMMP2CHRM1COMTADRA1A | |
| Oxyquinoline SCHEMBL253313 | 0.94 | TSHR (1.00) | TSHRMMP2CHRM1COMTADRA1A | |
| Oxyquinoline SCHEMBL4396353 | 0.92 | TSHR (0.88) | TSHRMMP2CHRM1COMTADRA1A | |
| Oxyquinoline SCHEMBL7187628 | 0.92 | TSHR (0.88) | TSHRMMP2CHRM1COMTADRA1A | |
| Oxyquinoline SCHEMBL23522696 | 0.91 | TSHR (0.95) | TSHRMMP2CHRM1COMTADRA1A | |
| Oxyquinoline SCHEMBL21195162 | 0.91 | TSHR (0.95) | TSHRMMP2CHRM1COMTADRA1A | |
| Oxyquinoline SCHEMBL20703753 | 0.91 | TSHR (0.95) | TSHRMMP2CHRM1COMTADRA1A | |
| Oxyquinoline SCHEMBL22467701 | 0.91 | TSHR (0.95) | TSHRMMP2CHRM1COMTADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6583583-B1 | Organic el material | NIPPON STEEL CHEMICAL CO., LTD. (JP) | 2003-06-24 | — | — | US | disclosed |