SCHEMBL7187685

SCHEMBL7187685

CO[Si](C(C)OCC1CO1)(C(C)OCC1CO1)C(C)OCC1CO1

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.38
TSHR P16473 2/20 0.35
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.34
TDP1 Q9NUW8 1/20 0.32
TP53 P04637 1/20 0.32
CYP3A4 P08684 1/20 0.32
GLA P06280 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL231370 0.84 ALDH1A1 (0.38) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL230964 0.84 ALDH1A1 (0.38) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL6635538 0.84 ALDH1A1 (0.38) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL7183177 0.81 SMN1; SMN2 (0.36) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL9300846 0.79 SMN1; SMN2 (0.35) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL28637747 0.78 ALDH1A1 (0.39) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL7186777 0.77 ALDH1A1 (0.37) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL11263044 0.77 SMN1; SMN2 (0.37) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL25209304 0.75 SMN1; SMN2 (0.33) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL2556581 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0620255-B1 Antifogging abrasion resistant coating composition and synthetic resin article coated therewith LUCKY LTD (KR) 2002-02-27 EP claimed
EP-0620255-A1 Antifogging abrasion resistant coating composition and synthetic resin article coated therewith LUCKY LTD. (KR) 1994-10-19 EP claimed
US-6586502-B2 Articles coated with the cured composition to provide scratch and abrasion resistance, protective or hard coating DOW GLOBAL TECHNOLOGIES INC. 2003-07-01 US disclosed
EP-0620255-B1 Antifogging abrasion resistant coating composition and synthetic resin article coated therewith LUCKY LTD (KR) 2002-02-27 EP disclosed
US-20020022682-A1 Inorganic/organic compositions DOW CHEMICAL COMPANY, THE 2002-02-21 US disclosed
US-5679458-A COATING COMPRISES AMINO FUNCTIONAL ORGANOSILANE, ACRYLIC COPOLYMER, CURING CATALYST; AUTOMOBILE MIRRORS, LENSES LUCKY LIMITED (KR) 1997-10-21 US disclosed
US-5414093-A Hydrolyzable and polymerizable silanes FRAUNHOFER-GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN (DE) 1995-05-09 US disclosed
EP-0620255-A1 Antifogging abrasion resistant coating composition and synthetic resin article coated therewith LUCKY LTD. (KR) 1994-10-19 EP disclosed
US-RE32272-E EPOXY GROUP-CONTAINING SILANE COMPOUND, POLYHDRIC ALCOHOL, POLYMER AND CURING AGENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-10-28 US disclosed
US-4594379-A Containing an organosilicon compound in photoinitiator blend NIPPON SHEET GLASS CO., LTD. (JP) 1986-06-10 US disclosed
US-4522966-A CURABLE MIXTURE OF GLYCIDYL-CONTAINING ACRYLIC POLYMER, A POLYOXYALKYLENE GLYCOL AND CATALYST NIPPON SHEET GLASS CO., LTD. (JP) 1985-06-11 US disclosed
US-4405679-A ADDITION POLYMER, POLYSILOXANE NIPPON SHEET GLASS CO. LTD. (JP) 1983-09-20 US disclosed
US-4394177-A Coating composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-07-19 US disclosed