SCHEMBL6635538

SCHEMBL6635538

CO[Si](OC)(C(C)OCC1CO1)C(C)OCC1CO1

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.38
TSHR P16473 2/20 0.35
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.34
TDP1 Q9NUW8 1/20 0.32
TP53 P04637 1/20 0.32
CYP3A4 P08684 1/20 0.32
GLA P06280 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL230964 0.84 ALDH1A1 (0.38) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL231370 0.84 ALDH1A1 (0.38) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL7187685 0.84 ALDH1A1 (0.38) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL6633116 0.81 SMN1; SMN2 (0.36) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL9300846 0.79 SMN1; SMN2 (0.35) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL28637747 0.78 ALDH1A1 (0.39) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL6632735 0.77 ALDH1A1 (0.37) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL11263044 0.77 SMN1; SMN2 (0.37) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL25209304 0.75 SMN1; SMN2 (0.33) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL635723 0.73 ALDH1A1 (0.46) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0620255-B1 Antifogging abrasion resistant coating composition and synthetic resin article coated therewith LUCKY LTD (KR) 2002-02-27 EP claimed
US-5917075-A Hydrolyzable and polymerizable silanes FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG, E.V. (DE) 1999-06-29 US claimed
US-5674941-A CURABLE PROTECTIVE COATING FOR OPTICAL ARTICLES COMPRISING AN AMINE-CONTAINING SILANE AND AN ACRYLIC COPOLYMER HAVING PENDANT HYDROXY, EPOXY, AMINO AND/OR SILANE GROUPS; ANTIFOGGING AGENTS; ADHESION TO POLYCARBONATES; NONABRASIVE LUCKY LIMITED (KR) 1997-10-07 US claimed
EP-0620255-A1 Antifogging abrasion resistant coating composition and synthetic resin article coated therewith LUCKY LTD. (KR) 1994-10-19 EP claimed
US-9745391-B2 Compounds containing (meth)acrylate groups and sulfonate or sulfate groups, polymers and condensates therefrom and use of the polymers and condensates Fraunhofer-Gesellschaft zur Föderung der angewandten Forschung e.V. (DE) 2017-08-29 US disclosed
US-20160297901-A1 Compounds containing (meth)acrylate groups and sulfonate or sulfate groups, polymers and condensates therefrom and use of the polymers and condensates Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2016-10-13 US disclosed
US-9353226-B2 Compounds containing (meth)acrylate groups and sulfonate or sulfate groups, polymers and condensates made therefrom and use of the polymers and condensates Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2016-05-31 US disclosed
US-20140088279-A1 Compounds containing (meth)acrylate groups and sulfonate or sulfate groups, polymers and condensates made therefrom and use of the polymers and condensates Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2014-03-27 US disclosed
EP-0939848-B1 METHODS FOR MANUFACTURING PACKAGING BOARD STORA ENSO OYJ (FI) 2004-05-19 EP disclosed
EP-0620255-B1 Antifogging abrasion resistant coating composition and synthetic resin article coated therewith LUCKY LTD (KR) 2002-02-27 EP disclosed
US-6307192-B1 CROSSLINKED POLYMERIC SILOXANE PROTECTIVE COATING; HEAT RESISTANCE; HERMETIC SEALING; WATERPROOFING, GREASE-TIGHT; MICROWAVES STORA ENSO OYJ (FI) 2001-10-23 US disclosed
US-6200644-B1 OVERCOATING PAPERBOARD OR CARDBOARD WITH PROTECTIVE SILICONE STORA ENSO OYI (FI) 2001-03-13 US disclosed
EP-0643752-A4 RESINOUS DENTAL COMPOSITION BASED ON POLYMERISABLE POLYSILOXANES. PROCTER & GAMBLE (US) 1994-06-03 EP disclosed
WO-1993007230-A1 RESINOUS DENTAL COMPOSITION BASED ON POLYMERISABLE POLYSILOXANES THE PROCTER & GAMBLE COMPANY (US) 1993-04-15 WO disclosed
US-4642266-A SCRATCH RESISTANCE AND WEATHERABILITY NIPPON SHEET GLASS CO., LTD. (JP) 1987-02-10 US disclosed
US-RE32272-E EPOXY GROUP-CONTAINING SILANE COMPOUND, POLYHDRIC ALCOHOL, POLYMER AND CURING AGENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-10-28 US disclosed
US-4594379-A Containing an organosilicon compound in photoinitiator blend NIPPON SHEET GLASS CO., LTD. (JP) 1986-06-10 US disclosed
US-4522966-A CURABLE MIXTURE OF GLYCIDYL-CONTAINING ACRYLIC POLYMER, A POLYOXYALKYLENE GLYCOL AND CATALYST NIPPON SHEET GLASS CO., LTD. (JP) 1985-06-11 US disclosed
US-4405679-A ADDITION POLYMER, POLYSILOXANE NIPPON SHEET GLASS CO. LTD. (JP) 1983-09-20 US disclosed
US-4394177-A Coating composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-07-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160297901-A1 Compounds containing (meth)acrylate groups and sulfonate or sulfate groups, polymers and condensates therefrom and use of the polymers and condensates AS3MT, GRM8, NPM1 ALDH1A1 3320/4885TSHR 1985/4885MAPK1 3249/4885
US-20140088279-A1 Compounds containing (meth)acrylate groups and sulfonate or sulfate groups, polymers and condensates made therefrom and use of the polymers and condensates AS3MT, TST, ALG3 ALDH1A1 1583/4885TSHR 3413/4885MAPK1 2242/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.