SCHEMBL7187760

SCHEMBL7187760

O=C1OC(=O)Oc2cc(O)ccc2O1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.45
TYR P14679 5/20 0.41
MAOA P21397 4/20 0.40
MAOB P27338 4/20 0.40
CA12 O43570 1/20 0.39
MCL1 Q07820 1/20 0.39
CA9 Q16790 1/20 0.39
CISD1 Q9NZ45 1/20 0.39
ESR1 P03372 3/20 0.39
ESR2 Q92731 3/20 0.39
UGT1A1 P22309 1/20 0.38
MAPT P10636 2/20 0.38
MEN1 O00255 1/20 0.38
HPGD P15428 1/20 0.38
CYP2C19 P33261 1/20 0.38
HTT P42858 1/20 0.38
RECQL P46063 1/20 0.38
BLM P54132 1/20 0.38
SMAD3 P84022 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4735618 0.83
SCHEMBL2456367 0.76 PTPRC (0.38) CA12CA9MAPTMEN1HTT
SCHEMBL14435757 0.76 CYP3A4 (0.48) CYP3A4TYRMAOAMAOBCA12
SCHEMBL18417129 0.76 AHR (0.54) CYP3A4TYRMAOAMAOBCA12
SCHEMBL14259795 0.75 MAOA (0.49) TYRMAOAMAOBMCL1CISD1
SCHEMBL9874879 0.73 MAOB (0.40) MAOAMAOBCA9HTTKDM4E
SCHEMBL5711966 0.73 MAPT (0.42) CYP3A4CA12CA9MAPTMEN1
SCHEMBL8760917 0.72 AHR (0.31) CYP3A4MAPTMEN1HPGDCYP2C19
SCHEMBL10448868 0.71 AHR (0.74) CYP3A4MAPTMEN1HPGDHTT
SCHEMBL10448864 0.71 AHR (0.74) CYP3A4MAPTMEN1HPGDHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1304924-A2 COMPOSITIONS FOR REPELLING CRAWLING INSECTS Bayer Aktiengesellschaft (DE) 2003-05-02 EP disclosed
WO-2002005646-A2 COMPOSITIONS FOR REPELLING CRAWLING INSECTS S.C. JOHNSON & SON, INC. (US) (US) 2002-01-24 WO disclosed