SCHEMBL8760917

SCHEMBL8760917

O=C1OC(=O)Oc2ccc3cc2OC(=O)OC(=O)Oc2cc(ccc2O1)C3O

nearest known ligand 0.33

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
AHR P35869 2/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
KDM4E B2RXH2 1/20 0.30
TP53 P04637 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
GAA P10253 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C9 P11712 1/20 0.30
ALOX12 P18054 1/20 0.30
CYP2C19 P33261 1/20 0.30
HTT P42858 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7187760 0.72 CYP3A4 (0.45) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL2456367 0.72 PTPRC (0.38) AHRMEN1KMT2AMAPTHTT
SCHEMBL5711966 0.68 MAPT (0.42) AHRMEN1KMT2AALDH1A1MAPT
SCHEMBL9874879 0.68 MAOB (0.40) ALDH1A1KDM4EGAAHTT
SCHEMBL7073349 0.67 POLB (0.42) AHRMEN1KMT2AMAPTALOX12
SCHEMBL9407361 0.67 ALDH1A1 (0.35) AHRMEN1KMT2AALDH1A1MAPT
SCHEMBL7186528 0.65 ALDH1A1 (0.52) AHRALDH1A1HPGDKDM4E
SCHEMBL5669943 0.65 TYMS (0.36)
SCHEMBL5285168 0.65 ALOX15 (0.43) AHR
SCHEMBL2468681 0.64 CA12 (0.41) MEN1KMT2AALDH1A1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0467258-B1 Copolymerisable composition, curable resin composition containing this and their use THERA GES FUER PATENTE (DE) 1997-06-04 EP disclosed
EP-0467258-A2 Copolymerisable composition, curable resin composition containing this and their use THERA Patent GmbH & Co. KG Gesellschaft für industrielle Schutzrechte (DE) 1992-01-22 EP disclosed