SCHEMBL718797

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29570020	1.00	PTGER4 (0.64)	PTGER4GPR3KDM4EPSEN1PSEN2
	SCHEMBL31711447	0.91	CYP2A6 (0.53)	PTGER4KDM4EPSEN1PSEN2APH1B
	SCHEMBL2713434	0.91	CYP2A6 (0.53)	PTGER4KDM4EPSEN1PSEN2APH1B
	SCHEMBL11180624	0.89	GPR3 (0.57)	PTGER4GPR3KDM4EPSEN1PSEN2
	Thiosemicarbazide SCHEMBL28053857	0.86	PTGER4 (0.51)	PTGER4GPR3KDM4EPSEN1PSEN2
	SCHEMBL14366792	0.85	GPR3 (0.61)	PTGER4GPR3KDM4EPSEN1PSEN2
	SCHEMBL30489261	0.85	PTGER4 (0.50)	PTGER4GPR3KDM4EPSEN1PSEN2
	SCHEMBL4687926	0.82	PTGER4 (0.72)	PTGER4KDM4EPSEN1PSEN2APH1B
	SCHEMBL29749450	0.82	PTGER4 (0.72)	PTGER4KDM4EPSEN1PSEN2APH1B
	SCHEMBL22166470	0.82	PTGER4 (0.56)	PTGER4KDM4EPSEN1PSEN2APH1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 441 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.